Recombinant Human BLM Protein, GST-tagged
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| Cat.No. : | BLM-241H |
| Product Overview : | Human BLM partial ORF ( NP_000048, 1196 a.a. - 1295 a.a.) recombinant protein with GST-tag at N-terminal. |
| Description : | The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3-5 helicase activity. The normal protein may act to suppress inappropriate recombination. |
| Source : | Wheat Germ |
| Species : | Human |
| Tag : | GST |
| Form : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Molecular Mass : | 36.74 kDa |
| AA Sequence : | SSVKKQKALV AKVSQREEMV KKCLGELTEV CKSLGKVFGV HYFNIFNTVT LKKLAESLSS DPEVLLQIDG VTEDKLEKYG AEVISVLQKY SEWTSPAEDS |
| Notes : | Best use within three months from the date of receipt of this protein. |
| Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Figure : |
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| Gene Name : | BLM Bloom syndrome, RecQ helicase-like [ Homo sapiens ] |
| Official Symbol : | BLM |
| Synonyms : | BLM; Bloom syndrome, RecQ helicase-like; Bloom syndrome; Bloom syndrome protein; BS; RECQ2; RECQL3; recQ protein-like 3; DNA helicase, RecQ-like type 2; RECQL2; MGC126616; MGC131618; MGC131620; |
| Gene ID : | 641 |
| mRNA Refseq : | NM_000057 |
| Protein Refseq : | NP_000048 |
| MIM : | 604610 |
| UniProt ID : | P54132 |
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