Recombinant Human BPNT1, GST-tagged
Cat.No. : | BPNT1-10277H |
Product Overview : | Recombinant Human BPNT1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
Availability | September 20, 2024 |
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Description : | BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntases physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-325a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | BPNT1 3(2), 5-bisphosphate nucleotidase 1 [ Homo sapiens ] |
Official Symbol : | BPNT1 |
Synonyms : | BPNT1; 3(2), 5-bisphosphate nucleotidase 1; 3(2),5-bisphosphate nucleotidase 1; BPntase; PAP-inositol-1,4-phosphatase; bisphosphate 3-nucleotidase 1; PIP; |
Gene ID : | 10380 |
mRNA Refseq : | NM_006085 |
Protein Refseq : | NP_006076 |
MIM : | 604053 |
UniProt ID : | O95861 |
Chromosome Location : | 1q42 |
Pathway : | Biological oxidations, organism-specific biosystem; Cytosolic sulfonation of small molecules, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Phase II conjugation, organism-specific biosystem; Sulfur metabolism, organism-specific biosystem; Sulfur metabolism, conserved biosystem; |
Function : | 3(2),5-bisphosphate nucleotidase activity; hydrolase activity; magnesium ion binding; |
Products Types
◆ Recombinant Protein | ||
BPNT1-667R | Recombinant Rat BPNT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
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BPNT1-1080M | Recombinant Mouse BPNT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
BPNT1-2092C | Recombinant Chicken BPNT1 | +Inquiry |
Bpnt1-1077M | Recombinant Mouse Bpnt1 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
BPNT1-8415HCL | Recombinant Human BPNT1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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