Recombinant Human BRMS1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: BRMS1-1591H
• Product Overview: BRMS1 MS Standard C13 and N15-labeled recombinant protein (NP_056214) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 28.5 kDa
• AA Sequence: MPVQPPSKDTEEMEAEGDSAAEMNG EEEESEEERSGSQTESEEESSEMDD EDYERRRSECVSEMLDLEKQFSELK EKLFRERLSQLRLRLEEVGAERAPE YTEPLGGLQRSLKIRIQVAGIYKGF CLDVIRNKYECELQGAKQHLESEKL LLYDTLQGELQERIQRLEEDRQSLD LSSEWWDDKLHARGSSRSWDSLPPS KRKKAPLVSGPYIVYMLQEIDILED WTAIKKARAAVSPQKRKSDGPTRTR PLEQKLISEEDLAANDILDYKDDDD KV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: BRMS1 breast cancer metastasis suppressor 1 [ Homo sapiens (human) ]
• Official Symbol: BRMS1
• Synonyms: BRMS1; breast cancer metastasis suppressor 1; breast cancer metastasis-suppressor 1; DKFZP564A063; DKFZp564A063
• Gene ID: 25855
• mRNA Refseq: NM_015399
• Protein Refseq: NP_056214
• MIM: 606259
• UniProt ID: Q9HCU9