Recombinant Human BSND Protein, GST-tagged

• Cat.No.: BSND-360H
• Product Overview: Human BSND full-length ORF (1 a.a. - 320 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. Mutations in this gene have been associated with Bartter syndrome with sensorineural deafness.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 61.6 kDa
• AA Sequence: MADEKTFRIGFIVLGLFLLALGTFL MSHDRPQVYGTFYAMGSVMVIGGII WSMCQCYPKITFVPADSDFQGILSP KAMGLLENGLAAEMKSPSPQPPYVR LWEEAAYDQSLPDFSHIQMKVMSYS EDHRSLLAPEMGQPKLGTSDGGEGG PGDVQAWMEAAVVIHKGSDESEGER RLTQSWPGPLACPQGPAPLASFQDD LDMDSSEGSSPNASPHDREEACSPQ QEPQGCRCPLDRFQDFALIDAPTLE DEPQEGQQWEIALPNNWQRYPRTKV EEKEASDTGGEEPEKEEEDLYYGLP DGAGDLLPDKELGFEPDTQG
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: BSND Bartter syndrome, infantile, with sensorineural deafness (Barttin) [ Homo sapiens ]
• Official Symbol: BSND
• Synonyms: BSND; Bartter syndrome, infantile, with sensorineural deafness (Barttin); deafness, autosomal recessive 73 , DFNB73; barttin; BART; deafness, autosomal recessive 73; DFNB73; MGC119283; MGC119284; MGC119285
• Gene ID: 7809
• mRNA Refseq: NM_057176
• Protein Refseq: NP_476517
• MIM: 606412
• UniProt ID: Q8WZ55