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Recombinant Human C4BPA protein, His-tagged

Cat.No. : C4BPA-42H
Product Overview : Recombinant Human C4BPA(49 a.a. - 597 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.
  • Specification
  • Gene Information
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Description : This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster.
Source : Wheat Germ
Species : Human
Tag : GST
Form : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass : 86.13 kDa
AA Sequence : NCGPPPTLSFAAPMDITLTETRFKT GTTLKYTCLPGYVRSHSTQTLTCNS DGEWVYNTFCIYKRCRHPGELRNGQ VEIKTDLSFGSQIEFSCSEGFFLIG STTSRCEVQDRGVGWSHPLPQCEIV KCKPPPDIRNGRHSGEENFYAYGFS VTYSCDPRFSLLGHASISCTVENET IGVWRPSPPTCEKITCRKPDVSHGE MVSGFGPIYNYKDTIVFKCQKGFVL RGSSVIHCDADSKWNPSPPACEPNS CINLPDIPHASWETYPRPTKEDVYV VGTVLRYRCHPGYKPTTDEPTTVIC QKNLRWTPYQGCEALCCPEPKLNNG EITQHRKSRPANHCVYFYGDEISFS CHETSRFSAICQGDGTWSPRTPSCG DICNFPPKIAHGHYKQSSSYSFFKE EIIYECDKGYILVGQAKLSCSYSHW SAPAPQCKALCRKPELVNGRLSVDK DQYVEPENVTIQCDSGYGVVGPQSI TCSGNRTWYPEVPKCEWETPEGCEQ VLTGKRLMQCLPNPEDVKMALEVYK LSLEIEQLELQRDSARQSTLDKEL
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name : C4BPA complement component 4 binding protein, alpha [ Homo sapiens ]
Official Symbol : C4BPA
Synonyms : C4BPA; complement component 4 binding protein, alpha; C4BP, complement component 4 binding protein, alpha; C4b-binding protein alpha chain; proline-rich protein; PRP; C4BP;
Gene ID : 722
mRNA Refseq : NM_000715
Protein Refseq : NP_000706
MIM : 120830
UniProt ID : P04003
Chromosome Location : 1q32
Pathway : CD40/CD40L signaling, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Pertussis, organism-specific biosystem;
Function : protein binding;

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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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