Recombinant Human CA11 Protein, GST-Tagged

• Cat.No.: CA11-0231H
• Product Overview: Human CA11 full-length ORF (AAH02662.1, 1 a.a. - 328 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 61.71 kDa
• AA Sequence: MGAAARLSAPRALVLWAALGAAAHI GPAPDPEDWWSYKDNLQGNFVPGPP FWGLVNAAWSLCAVGKRQSPVDVEL KRVLYDPFLPPLRLSTGGEKLRGTL YNTGRHVSFLPAPRPVVNVSGGPLL YSHRLSELRLLFGARDGAGSEHQIN HQGFSAEVQLIHFNQELYGNFSAAS RGPNGLAILSLFVNVASTSNPFLSR LLNRDTITRISYKNDAYFLQDLSLE LLFPESFGFITYQGSLSTPPCSETV TWILIDRALNITSLQMHSLRLLSQN PPSQIFQSLSGNSRPLQPLAHRALR GNRDPRHPERRCRGPNYRLHVDGVP HGR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CA11 carbonic anhydrase XI [ Homo sapiens ]
• Official Symbol: CA11
• Synonyms: CA11; carbonic anhydrase XI; carbonic anhydrase-related protein 11; CA RP XI; carbonic anhydrase related protein 2; carbonic anhydrase related protein XI; CARP2; CARPX1; CA-XI; CARP-2; CARP XI; CA-RP II; carbonic anhydrase-related protein 2; carbonic anhydrase-related protein XI
• Gene ID: 770
• mRNA Refseq: NM_001217
• Protein Refseq: NP_001208
• MIM: 604644
• UniProt ID: O75493