Recombinant Human CACNB1 Protein, GST-Tagged
Cat.No. : | CACNB1-0270H |
Product Overview : | Human CACNB1 full-length ORF (NP_000714.3, 1 a.a. - 598 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 92.1 kDa |
AA Sequence : | MVQKTSMSRGPYPPSQEIPMEVFDP SPQGKYSKRKGRFKRSDGSTSSDTT SNSFVRQGSAESYTSRPSDSDVSLE EDREALRKEAERQALAQLEKAKTKP VAFAVRTNVGYNPSPGDEVPVQGVA ITFEPKDFLHIKEKYNNDWWIGRLV KEGCEVGFIPSPVKLDSLRLLQEQK LRQNRLGSSKSGDNSSSSLGDVVTG TRRPTPPASAKQKQKSTEHVPPYDV VPSMRPIILVGPSLKGYEVTDMMQK ALFDFLKHRFDGRISITRVTADISL AKRSVLNNPSKHIIIERSNTRSSLA EVQSEIERIFELARTLQLVALDADT INHPAQLSKTSLAPIIVYIKITSPK VLQRLIKSRGKSQSKHLNVQIAASE KLAQCPPEMFDIILDENQLEDACEH LAEYLEAYWKATHPPSSTPPNPLLN RTMATAALAASPAPVSNLQGPYLAS GDQPLERATGEHASMHEYPGELGQP PGLYPSSHPPGRAGTLRALSRQDTF DADTPGSRNSAYTELGDSCVDMETD PSEGPGLGDPAGGGTPPARQGSWED EEEDYEEELTDNRNRGRNKARYCAE GGGPVLGRNKNELEGWGRGVYIR |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CACNB1 calcium channel, voltage-dependent, beta 1 subunit [ Homo sapiens ] |
Official Symbol : | CACNB1 |
Synonyms : | CACNB1; calcium channel, voltage-dependent, beta 1 subunit; CACNLB1; voltage-dependent L-type calcium channel subunit beta-1; calcium channel, L type, beta 1 polypeptide; calcium channel voltage-dependent subunit beta 1; dihydropyridine-sensitive L-type, calcium channel beta-1 subunit; CAB1; CCHLB1; MGC41896; |
Gene ID : | 782 |
mRNA Refseq : | NM_000723 |
Protein Refseq : | NP_000714 |
MIM : | 114207 |
UniProt ID : | Q02641 |
Products Types
◆ Recombinant Protein | ||
Cacnb1-736M | Recombinant Mouse Cacnb1 Protein, MYC/DDK-tagged | +Inquiry |
CACNB1-2262H | Recombinant Human CACNB1 Protein, MYC/DDK-tagged | +Inquiry |
CACNB1-1173M | Recombinant Mouse CACNB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CACNB1-732R | Recombinant Rat CACNB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CACNB1-2619M | Recombinant Mouse CACNB1 Protein | +Inquiry |
◆ Lysates | ||
CACNB1-7903HCL | Recombinant Human CACNB1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionCACNB1 can enhance the open probability of associated calcium channels, thereby modulating calcium influx into cells.
Dysfunctions or mutations in CACNB1 have been linked to certain cardiac and neurological disorders.
CACNB1 interacts with the alpha-1 subunit of calcium channels, and potentially other regulatory proteins, to modulate channel activity.
Certain mutations in the CACNB1 gene can lead to altered channel activity, potentially causing or contributing to disease states.
CACNB1 acts as an auxiliary subunit of voltage-gated calcium channels, modulating their activity and surface expression.
CACNB1 is expressed in a variety of tissues, but it is particularly prevalent in the heart and central nervous system.
Post-translational modifications like phosphorylation have been identified on CACNB1, which can influence its function and interactions.
Customer Reviews (3)
Write a reviewFast turnaround, crucial for meeting project deadlines.
Dependable source for all our protein research needs.
Efficient sample handling, simplifies our workflow.
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