Recombinant Human CADM4 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : CADM4-6655H
Product Overview : CADM4 MS Standard C13 and N15-labeled recombinant protein (NP_660339) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : CADM4 (Cell Adhesion Molecule 4) is a Protein Coding gene. Diseases associated with CADM4 include Small Intestine Adenocarcinoma and Neuropathy, Congenital Hypomyelinating, 1, Autosomal Recessive. An important paralog of this gene is CADM1.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 42.6 kDa
AA Sequence : MGRARRFQWPLLLLWAAAAGPGAGQ EVQTENVTVAEGGVAEITCRLHQYD GSIVVIQNPARQTLFFNGTRALKDE RFQLEEFSPRRVRIRLSDARLEDEG GYFCQLYTEDTHHQIATLTVLVAPE NPVVEVREQAVEGGEVELSCLVPRS RPAATLRWYRDRKELKGVSSSQENG KVWSVASTVRFRVDRKDDGGIIICE AQNQALPSGHSKQTQYVLDVQYSPT ARIHASQAVVREGDTLVLTCAVTGN PRPNQIRWNRGNESLPERAEAVGET LTLPGLVSADNGTYTCEASNKHGHA RALYVLVVYDPGAVVEAQTSVPYAI VGGILALLVFLIICVLVGMVWCSVR QKGSYLTHEASGLDEQGEAREAFLN GSDGHKRKEEFFITRTRPLEQKLIS EEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : CADM4 cell adhesion molecule 4 [ Homo sapiens (human) ]
Official Symbol : CADM4
Synonyms : CADM4; cell adhesion molecule 4; IGSF4C, immunoglobulin superfamily, member 4C; Necl 4; nectin like 4; SynCAM4; TSLL2; TSLC1-like 2; nectin-like 4; TSLC1-like protein 2; nectin-like protein 4; immunoglobulin superfamily member 4C; immunoglobulin superfamily, member 4C; NECL4; IGSF4C; Necl-4; synCAM4;
Gene ID : 199731
mRNA Refseq : NM_145296
Protein Refseq : NP_660339
MIM : 609744
UniProt ID : Q8NFZ8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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05/08/2021

    Reliable recombinant proteins are a must for researchers.

    09/02/2019

      These product simplify our research.

      12/12/2018

        Our lab relies on the product for consistency.

        Q&As (5)

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        Why is immunoprecipitation important for studying CADM4-related protein interactions? 02/14/2022

        Immunoprecipitation allows the isolation of CADM4 and its binding partners, helping identify proteins that interact with CADM4 and revealing its functional associations.

        Can you elaborate on the role of Cadm4 in cell signaling pathways, and how do its interactions impact intracellular signaling cascades? 03/05/2021

        Cadm4's interactions extend beyond cell adhesion to impact intracellular signaling pathways. Through its adhesive properties, Cadm4 can initiate signaling events that influence cell proliferation, differentiation, and other cellular processes, making it an integral component of cellular signaling networks.

        Can you discuss the molecular structure of Cadm4 and its interactions with other proteins or ligands in cellular adhesion processes? 04/01/2020

        Cadm4 has a complex molecular structure involving extracellular domains for adhesion. It interacts with various proteins and ligands, facilitating cell adhesion and signaling.

        How does Cadm4's expression change during development, and what are its roles in tissue development and differentiation? 08/17/2019

        Cadm4 expression varies during development and contributes to tissue development and cellular differentiation, particularly in the nervous system.

        What are the current challenges in developing therapies targeting Cadm4, and what research directions are being explored to overcome these challenges? 10/11/2018

        The development of Cadm4-targeted therapies faces challenges related to precision and effectiveness. Ongoing research is focused on refining drug targeting strategies and gaining a deeper understanding of Cadm4's relevance in various disease contexts.

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