Recombinant Human CALCR Protein, GST-Tagged

• Cat.No.: CALCR-0296H
• Product Overview: Human CALCR full-length ORF (NP_001733.1, 1 a.a. - 474 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 81.7 kDa
• AA Sequence: MRFTFTSRCLALFLLLNHPTPILPA FSNQTYPTIEPKPFLYVVGRKKMMD AQYKCYDRMQQLPAYQGEGPYCNRT WDGWLCWDDTPAGVLSYQFCPDYFP DFDPSEKVTKYCDEKGVWFKHPENN RTWSNYTMCNAFTPEKLKNAYVLYY LAIVGHSLSIFTLVISLGIFVFFRS LGCQRVTLHKNMFLTYILNSMIIII HLVEVVPNGELVRRDPVSCKILHFF HQYMMACNYFWMLCEGIYLHTLIVV AVFTEKQRLRWYYLLGWGFPLVPTT IHAITRAVYFNDNCWLSVETHLLYI IHGPVMAALVVNFFFLLNIVRVLVT KMRETHEAESHMYLKAVKATMILVP LLGIQFVVFPWRPSNKMLGKIYDYV MHSLIHFQGFFVATIYCFCNNEVQT TVKRQWAQFKIQWNQRWGRRPSNRS ARAAAAAAEAGDIPIYICHQELRNE PANNQGEESAEIIPLNIIEQESSA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CALCR calcitonin receptor [ Homo sapiens ]
• Official Symbol: CALCR
• Synonyms: CALCR; calcitonin receptor; CTR; CRT; CT-R; CTR1
• Gene ID: 799
• mRNA Refseq: NM_001164737
• Protein Refseq: NP_001158209
• MIM: 114131
• UniProt ID: P30988