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Recombinant Human CAMKK2 Protein, GST-Tagged

Cat.No. : CAMKK2-0341H
Product Overview : Human CAMKK2 full-length ORF (NP_705719.2, 1 a.a. - 541 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 86 kDa
AA Sequence : MSSCVSSQPSSNRAAPQDELGGRGS SSSESQKPCEALRGLSSLSIHLGME SFIVVTECEPGCAVDLGLARDRPLE ADGQEVPLDTSGSQARPHLSGRKLS LQERSQGGLAAGGSLDMNGRCICPS LPYSPVSSPQSSPRLPRRPTVESHH VSITGMQDCVQLNQYTLKDEIGKGS YGVVKLAYNENDNTYYAMKVLSKKK LIRQAGFPRRPPPRGTRPAPGGCIQ PRGPIEQVYQEIAILKKLDHPNVVK LVEVLDDPNEDHLYMVFELVNQGPV MEVPTLKPLSEDQARFYFQDLIKGI EYLHYQKIIHRDIKPSNLLVGEDGH IKIADFGVSNEFKGSDALLSNTVGT PAFMAPESLSETRKIFSGKALDVWA MGVTLYCFVFGQCPFMDERIMCLHS KIKSQALEFPDQPDIAEDLKDLITR MLDKNPESRIVVPEIKLHPWVTRHG AEPLPSEDENCTLVEVTEEEVENSV KHIPSLATVILVKTMIRKRSFGNPF EGSRREERSLSAPGNLLTKQGSEDN LQGTDPPPVGEEEVLL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta [ Homo sapiens ]
Official Symbol : CAMKK2
Synonyms : CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2, beta; calcium/calmodulin-dependent protein kinase kinase 2; CAMKK; CAMKKB; KIAA0787; MGC15254; caM-KK 2; caM-KK beta; CAMKK beta protein; caM-kinase kinase 2; caM-kinase kinase beta; calcium/calmodulin-dependent protein kinase beta;
Gene ID : 10645
mRNA Refseq : NM_006549
Protein Refseq : NP_006540
UniProt ID : Q96RR4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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