Recombinant Human CAPN10 cell lysate
Cat.No. : | CAPN10-276HCL |
- Specification
- Gene Information
- Related Products
Description : | Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM) and located within the NIDDM1 region. Multiple alternative transcript variants encoding different isoforms have been described for this gene. |
Species : | Human |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name : | CAPN10 calpain 10 [ Homo sapiens ] |
Official Symbol : | CAPN10 |
Synonyms : | CAPN10; calpain 10; calpain-10; calpain-like protease CAPN10; calcium-activated neutral proteinase 10; CANP10; NIDDM1; |
Gene ID : | 11132 |
mRNA Refseq : | NM_023083 |
Protein Refseq : | NP_075571 |
MIM : | 605286 |
UniProt ID : | Q9HC96 |
Chromosome Location : | 2q37.3 |
Pathway : | Integrin-mediated cell adhesion, organism-specific biosystem; |
Function : | SNARE binding; calcium-dependent cysteine-type endopeptidase activity; cytoskeletal protein binding; peptidase activity; |
Products Types
◆ Recombinant Protein | ||
CAPN10-105C | Recombinant Cynomolgus Monkey CAPN10 Protein, His (Fc)-Avi-tagged | +Inquiry |
CAPN10-361H | Recombinant Human CAPN10 Protein, His-tagged | +Inquiry |
CAPN10-1214M | Recombinant Mouse CAPN10 Protein, His (Fc)-Avi-tagged | +Inquiry |
CAPN10-2691M | Recombinant Mouse CAPN10 Protein | +Inquiry |
CAPN10-29H | Recombinant Human CAPN10 Protein, GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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