Recombinant Human CAPN5 Protein, GST-Tagged

• Cat.No.: CAPN5-0366H
• Product Overview: Human CAPN5 full-length ORF (NP_004046.2, 1 a.a. - 640 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 99.6 kDa
• AA Sequence: MFSCVKPYEDQNYSALRRDCRRRKV LFEDPLFPATDDSLYYKGTPGPAVR WKRPKGICEDPRLFVDGISSHDLHQ GQVGNCWFVAACSSLASRESLWQKV IPDWKEQEWDPEKPNAYAGIFHFHF WRFGEWVDVVIDDRLPTVNNQLIYC HSNSRNEFWCALVEKAYAKLAGCYQ ALDGGNTADALVDFTGGVSEPIDLT EGDFANDETKRNQLFERMLKVHSRG GLISASIKAVTAADMEARLACGLVK GHAYAVTDVRKVRLGHGLLAFFKSE KLDMIRLRNPWGEREWNGPWSDTSE EWQKVSKSEREKMGVTVQDDGEFWM TFEDVCRYFTDIIKCRVINTSHLSI HKTWEEARLHGAWTLHEDPRQNRGG GCINHKDTFFQNPQYIFEVKKPEDE VLICIQQRPKRSTRREGKGENLAIG FDIYKVEENRQYRMHSLQHKAASSI YINSRSVFLRTDQPEGRYVIIPTTF EPGHTGEFLLRVFTDVPSNCRELRL DEPPHTCWSSLCGYPQLVTQVHVLG AAGLKDSPTGANSYVIIKCEGDKVR SAVQKGTSTPEYNVKGIFYRKKLSQ PITVQVWNHRVLKDEFLGQVHLKAD PDNLQALHTLHLRDRNSRQPSNLPG TVAVHILSSTSLMAV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CAPN5 calpain 5 [ Homo sapiens ]
• Official Symbol: CAPN5
• Synonyms: CAPN5; calpain 5; calpain-5; HTRA3; nCL 3; new calpain 3; calpain htra-3; nCL-3; FLJ46245
• Gene ID: 726
• mRNA Refseq: NM_004055
• Protein Refseq: NP_004046
• MIM: 602537
• UniProt ID: O15484