Recombinant Human CAPRIN1 Protein, MYC/DDK-tagged

• Cat.No.: CAPRIN1-026H
• Product Overview: Recombinant protein of human cell cycle associated protein 1 (CAPRIN1), transcript variant 1 with C-MYC/DDK tag was expressed in HEK293T.

Specification

• Description: May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Molecular Mass: 78.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Storage: Store at –80 centigrade. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: CAPRIN1 cell cycle associated protein 1 [ Homo sapiens (human) ]
• Official Symbol: CAPRIN1
• Synonyms: GPIAP1; GPIP137; GRIP137; M11S1; p137GPI; RNG105; caprin-1; GPI-anchored membrane protein 1; GPI-anchored protein p137; GPI-p137; RNA granule protein 105; activation/proliferation-associated protein 1; caprin 1; cytoplasmic activation- and proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein-1; membrane component chromosome 11 surface marker 1
• Gene ID: 4076
• mRNA Refseq: NM_005898
• Protein Refseq: NP_005889
• MIM: 601178
• UniProt ID: Q14444