Recombinant Human Carboxypeptidase B2 (Plasma), His-tagged

• Cat.No.: CPB2-3906H
• Product Overview: A DNA sequence encoding the human CPB2 ( NP_001863.2 ) extracellular domain ( Met 1-Val 423 ) was expressed, fused with a polyhistidine tag at the C-terminus.

Specification

• Species: Human
• Source: Human
• Tag: His
• Protein Length: 1-423 a.a.
• Description: Carboxypeptidase B2, also known as Carboxypeptidase U, Thrombin-activable fibrinolysis inhibitor, Plasma carboxypeptidase B, CPB2, is a secreted protein which belongs to the peptidase M14 family. Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds.
• Form: Lyophilized from sterile PBS, pH 7.4
• Purity: > 97 % as determined by SDS-PAGE
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method
• Stability: Samples are stable for up to twelve months from date of receipt at -70°C.
• Predicted N terminal: Phe 23
• Molecular Mass: The recombinant human CPB2 consists of 412 amino acids and predictes a molecular mass of 47.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhCPB2 is approximately 45-50 kDa due to glycosylation.
• Storage: Store it under sterile conditions at -70°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage.

Gene Information

• Gene Name: CPB2 carboxypeptidase B2 (plasma) [ Homo sapiens ]
• Official Symbol: CPB2
• Synonyms: CPB2; carboxypeptidase B2 (plasma); CPU; PCPB; TAFI; carboxypeptidase B2; OTTHUMP00000018364; OTTHUMP00000018365; carboxypeptidase U; plasma carboxypeptidase B; carboxypeptidase B-like protein; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor; carboxypeptidase B2 (plasma, carboxypeptidase U)
• Gene ID: 1361
• mRNA Refseq: NM_001872
• Protein Refseq: NP_001863
• MIM: 603101
• UniProt ID: Q96IY4
• Chromosome Location: 13q14.11
• Pathway: Complement and Coagulation Cascades; Complement and coagulation cascades; Pancreatic secretion; Protein digestion and absorption
• Function: metal ion binding; metallocarboxypeptidase activity; metallopeptidase activity; peptidase activity; zinc ion binding