Recombinant Human CBLL1 Protein, GST-Tagged

• Cat.No.: CBLL1-0462H
• Product Overview: Human CBLL1 full-length ORF (BAB15544.1, 1 a.a. - 491 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant. [provided by RefSeq, Aug 2011]
• Molecular Mass: 80.9 kDa
• AA Sequence: MDHTDNELQGTNSSGSLGGLDVRRRIPIKLISKQANKAKPAPRTQRTINRMPAKAPPGDEEGFDYNEEERYDCKGGELFANQRRFPGHLFWDFQINILGEKDDTPVHFCDKCGLPIKIYGRMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQRDLQAHINHRHMRAGKPVTRASLENVHPPIAPPPTEIPERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTPSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHPDQTRYRPYYQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CBLL1 Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1 [ Homo sapiens ]
• Official Symbol: CBLL1
• Synonyms: CBLL1; Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1; Cas Br M (murine) ecotropic retroviral transforming sequence like 1; E3 ubiquitin-protein ligase Hakai; Casitas B lineage lymphoma like; FLJ23109; HAKAI; RNF188; c-Cbl-like protein 1; RING finger protein 188; E-cadherin binding protein E7; casitas B-lineage lymphoma-transforming sequence-like protein 1; Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1; MGC163401; MGC163403
• Gene ID: 79872
• mRNA Refseq: NM_024814
• Protein Refseq: NP_079090
• MIM: 606872
• UniProt ID: Q75N03