Recombinant Human CBLL1 Protein, GST-Tagged

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Recombinant Human CBLL1 Protein, GST-Tagged

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Cat.No. : CBLL1-0462H
Product Overview : Human CBLL1 full-length ORF (BAB15544.1, 1 a.a. - 491 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant. [provided by RefSeq, Aug 2011]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 80.9 kDa
AA Sequence : MDHTDNELQG TNSSGSLGGL DVRRRIPIKL ISKQANKAKP APRTQRTINR MPAKAPPGDE EGFDYNEEER YDCKGGELFA NQRRFPGHLF WDFQINILGE KDDTPVHFCD KCGLPIKIYG RMIPCKHVFC YDCAILHEKK GDKMCPGCSD PVQRIEQCTR GSLFMCSIVQ GCKRTYLSQR DLQAHINHRH MRAGKPVTRA SLENVHPPIA PPPTEIPERF IMPPDKHHMS HIPPKQHIMM PPPPLQHVPH EHYNQPHEDI RAPPAELSMA PPPPRSVSQE TFRISTRKHS NLITVPIQDD SNSGAREPPP PAPAPAHHHP EYQGQPVVSH PHHIMPPQQH YAPPPPPPPP ISHPMPHPPQ AAGTPHLVYS QAPPPPMTSA PPPITPPPGH IIAQMPPYMN HPPPGPPPPQ HGGPPVTAPP PHHYNPNSLP QFTEDQGTPS PPFTQPGGMS PGIWPAPRGP PPPPRLQGPP SQTPLPGPHH PDQTRYRPYY Q
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CBLL1 Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1 [ Homo sapiens ]
Official Symbol : CBLL1
Synonyms : CBLL1; Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1; Cas Br M (murine) ecotropic retroviral transforming sequence like 1; E3 ubiquitin-protein ligase Hakai; Casitas B lineage lymphoma like; FLJ23109; HAKAI; RNF188; c-Cbl-like protein 1; RING finger protein 188; E-cadherin binding protein E7; casitas B-lineage lymphoma-transforming sequence-like protein 1; Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1; MGC163401; MGC163403;
Gene ID : 79872
mRNA Refseq : NM_024814
Protein Refseq : NP_079090
MIM : 606872
UniProt ID : Q75N03

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