Recombinant Human CC2D1A, His-tagged

• Cat.No.: CC2D1A-26320TH
• Product Overview: Recombinant fragment, corresponding to amino acids 672-951 of Human CC2D1A with N terminal His tag; Predicted MWt 33 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 672-951 a.a.
• Description: This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.
• Conjugation: HIS
• Form: Lyophilised:Reconstitute with 106 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: GLSPGDLDVFVRFDFPYPNVEEAQKDKTSVIKNTDSPEFK EQFKLCINRSHRGFRRAIQTKGIKFEVVHKGGLFKTDR VLGTAQLKLDALEIACEVREILEVLDGRRPTGGRLEVM VRIREPLTAQQLETTTERWLVIDPVPAAVPTQVAGPKG KAPPVPAPARESGNRSARPLHSLSVLAFDQERLERKILALRQARRPVPPEVAQQYQDIMQRSQWQRAQLEQGGVGIRR EYAAQLERQLQFYTEAARRLGNDGSRDAAKEALYRRNL VESELQRLRR

Gene Information

• Gene Name: CC2D1A coiled-coil and C2 domain containing 1A [ Homo sapiens ]
• Official Symbol: CC2D1A
• Synonyms: CC2D1A; coiled-coil and C2 domain containing 1A; coiled-coil and C2 domain-containing protein 1A; FLJ20241; mental retardation; nonsyndromic; autosomal recessive; 3; MRT3
• Gene ID: 54862
• mRNA Refseq: NM_017721
• Protein Refseq: NP_060191
• MIM: 610055
• Uniprot ID: Q6P1N0
• Chromosome Location: 19p13.12
• Pathway: SIDS Susceptibility Pathways, organism-specific biosystem
• Function: DNA binding; signal transducer activity