Recombinant Human CC2D1A Protein, GST-Tagged

• Cat.No.: CC2D1A-0489H
• Product Overview: Human CC2D1A full-length ORF (NP_060191.3, 1 a.a. - 951 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.[provided by RefSeq, Oct 2009]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 130.5 kDa
• AA Sequence: MHKRKGPPGPPGRGAAAARQLGLLV DLSPDGLMIPEDGANDEELEAEFLA LVGGQPPALEKLKGKGPLPMEAIEK MASLCMRDPDEDEEEGTDEDDLEAD DDLLAELNEVLGEEQKASETPPPVA QPKPEAPHPGLETTLQERLALYQTA IESARQAGDSAKMRRYDRGLKTLEN LLASIRKGNAIDEADIPPPVAIGKG PASTPTYSPAPTQPAPRIASAPEPR VTLEGPSATAPASSPGLAKPQMPPG PCSPGPLAQLQSRQRDYKLAALHAK QQGDTTAAARHFRVAKSFDAVLEAL SRGEPVDLSCLPPPPDQLPPDPPSP PSQPPTPATAPSTTEVPPPPRTLLE ALEQRMERYQVAAAQAKSKGDQRKA RMHERIVKQYQDAIRAHKAGRAVDV AELPVPPGFPPIQGLEATKPTQQSL VGVLETAMKLANQDEGPEDEEDEVP KKQNSPVAPTAQPKAPPSRTPQSGS APTAKAPPKATSTRAQQQLAFLEGR KKQLLQAALRAKQKNDVEGAKMHLR QAKGLEPMLEASRNGLPVDITKVPP APVNKDDFALVQRPGPGLSQEAARR YGELTKLIRQQHEMCLNHSNQFTQL GNITETTKFEKLAEDCKRSMDILKQ AFVRGLPTPTARFEQRTFSVIKIFP DLSSNDMLLFIVKGINLPTPPGLSP GDLDVFVRFDFPYPNVEEAQKDKTS VIKNTDSPEFKEQFKLCINRSHRGF RRAIQTKGIKFEVVHKGGLFKTDRV LGTAQLKLDALEIACEVREILEVLD GRRPTGGRLEVMVRIREPLTAQQLE TTTERWLVIDPVPAAVPTQVAGPKG KAPPVPAPARESGNRSARPLHSLSV LAFDQERLERKILALRQARRPVPPE VAQQYQDIMQRSQWQRAQLEQGGVG IRREYAAQLERQLQFYTEAARRLGN DGSRDAAKEALYRRNLVESELQRLR R
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CC2D1A coiled-coil and C2 domain containing 1A [ Homo sapiens ]
• Official Symbol: CC2D1A
• Synonyms: CC2D1A; coiled-coil and C2 domain containing 1A; coiled-coil and C2 domain-containing protein 1A; FLJ20241; mental retardation; nonsyndromic; autosomal recessive; 3; MRT3; Akt kinase-interacting protein 1; putative NFkB activating protein; FRE under dual repression-binding protein 1; putative NF-kappa-B-activating protein 023N; mental retardation, nonsyndromic, autosomal recessive, 3; five repressor element under dual repression-binding protein 1; five prime repressor element under dual repression-binding protein 1; FREUD-1; Freud-1/Aki1; FLJ41160
• Gene ID: 54862
• mRNA Refseq: NM_017721
• Protein Refseq: NP_060191
• MIM: 610055
• UniProt ID: Q6P1N0