Recombinant Human CCDC22 Protein, GST-Tagged

• Cat.No.: CCDC22-0537H
• Product Overview: Human CCDC22 full-length ORF (ABW03374.1, 1 a.a. - 627 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein containing a coiled-coil domain. The encoded protein functions in the regulation of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) by interacting with COMMD (copper metabolism Murr1 domain-containing) proteins. The mouse orthologous protein has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. This human gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability. [provided by RefSeq, Aug 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 95.37 kDa
• AA Sequence: MEEADRILIHSLRQAGTAVPPDVQT LRAFTTELVVEAVVRCLRVINPAVG SGLSPLLPLAMSARFRLAMSLTQAC MDLGYPLELGYQNFLYPSEPDLRDL LLFLAERLPTDASEDADQPAGDSAI LLRAIGSQIRDQLALPWVPPHLRTP KLQHLQGSALQKPFHASRLVVPELS SRGEPREFQASPLLLPVPTQVPQPV GRVASLLEHHALQLCQQTGRDRPGD EDWVHRTSRLPPQEDTRAQRQRLQK QLTEHLRQSWGLLGAPIQARDLGEL LQAWGAGAKTGAPKGSRFTHSEKFT FHLEPQAQATQVSDVPATSRRPEQV TWAAQEQELESLREQLEGVNRSIEE VEADMKTLGVSFVQAESECRHSKLS TAEREQALRLKSRAVELLPDGTANL AKLQLVVENSAQRVIHLAGQWEKHR VPLLAEYRHLRKLQDCRELESSRRL AEIQELHQSVRAAAEEARRKEEVYK QLMSELETLPRDVSRLAYTQRILEI VGNIRKQKEEITKILSDTKELQKEI NSLSGKLDRTFAVTDELVFKDAKKD DAVRKAYKYLAALHENCSQLIQTIE DTGTIMREVRDLEEQIETELGKKTL SNLEKIREDYRALRQENAGLLGRVR EA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CCDC22 coiled-coil domain containing 22 [ Homo sapiens ]
• Official Symbol: CCDC22
• Synonyms: CCDC22; coiled-coil domain containing 22; chromosome X open reading frame 37, CXorf37; coiled-coil domain-containing protein 22; JM1; CXorf37
• Gene ID: 28952
• mRNA Refseq: NM_014008
• Protein Refseq: NP_054727
• MIM: 300859
• UniProt ID: O60826