Recombinant Human CCHCR1 Protein, GST-Tagged

• Cat.No.: CCHCR1-0600H
• Product Overview: Human CCHCR1 full-length ORF (BAA91016.1, 1 a.a. - 782 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein with five coiled-coil alpha-helical rod domains that is thought to act as a regulator of mRNA metabolism through its interaction with mRNA-decapping protein 4. It localizes to P-bodies, the site of mRNA metabolism, with an N-terminus that is required for this subcellular localization, suggesting it is a P-body component. Naturally occurring mutations in this gene are associated with psoriasis. [provided by RefSeq, May 2017]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 115 kDa
• AA Sequence: MFPPSGSTGLIPPSHFQARPLSTLP RMAPTWLSDIPLVQPPGHQDVSERR LDTQRPQVTMWERDVSSDRQEPGRR GRSWGLEGSQALSQQAEVIVRQLQE LRRLEEEVRLLRETSLQQKMRLEAQ AMELEALARAEKAGRAEAEGLRAAL AGAEVVRKNLEEGSQRELEEVQRLH QEQLSSLTQAHEEALSSLTSKAEGL EKSLSSLETRRAGEAKELAEAQREA ELLRKQLSKTQEDLEAQVTLVENLR KYVGEQVPSEVHSQTWELERQKLLE TMQHLQEDRDSLHATAELLQVRVQS LTHILALQEEELTRKVQPSDSLEPE FTRKCQSLLNRWREKVFALMVQLKA QELEHSDSVKQLKGQVASLQEKVTS QSQEQAILQRSLQDKAAEVEVERMG AKGLQLELSRAQEARRQWQQQTASA EEQLRLVVNAVSSSQIWLETTMAKV EGAAAQLPSLNNRLSYAVRKVHTIR GLIARKLALAQLRQESCPLPPPVTD VSLELQQLREERNRLDAELQLSARL IQQEVGRAREQGEAERQQLSKVAQQ LEQELQQTQESLASLGLQLEVARQG QQESTEEAASLRQELTQQQELYGQA LQEKVAEVETRLREQLSDTERRLNE ARREHAKAVVSLRQIQRRAAQEKER SQELRRLQEEARKEEGQRLARRLQE LERDKNLMLATLQQEGLLSRYKQQR LLTVLPSLLDKKKSVVSSPRPPECS ASAPVAAAVPTRESIKGSLSVLLDD LQDLSEAISKEEAVCQGDNLDRCSS SNPQMSS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CCHCR1 coiled-coil alpha-helical rod protein 1 [ Homo sapiens ]
• Official Symbol: CCHCR1
• Synonyms: CCHCR1; coiled-coil alpha-helical rod protein 1; C6orf18, chromosome 6 open reading frame 18; HCR; pg8; StAR-binding protein; putative gene 8 protein; alpha-helical coiled-coil rod protein; HCR (a-helix coiled-coil rod homologue); SBP; C6orf18; MGC126371; MGC126372
• Gene ID: 54535
• mRNA Refseq: NM_001105563
• Protein Refseq: NP_001099033
• MIM: 605310
• UniProt ID: Q8TD31