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Recombinant Human CCL23 protein

Cat.No. : CCL23-199H
Product Overview : Recombinant Human CCL23 protein was expressed in Escherichia coli.
  • Specification
  • Gene Information
  • Related Products
Description : CCL23 is a member of CC chemokine family and is encoded by CCL23 gene located on Chr.17 in humans, where near several other CC chemokines. Highly expressed in adult lung, liver, skeletal muscle and pancreas, this protein shows strong chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. It elicits the effects by binding to CCR1. CCL23 is reported that it can be cleaved into four forms: CCL23 (19-99), CCL23 (22-99), CCL23 (27-99), CCL23 (30-99).
Source : E.coli
Species : Human
Form : Lyophilized from a 0.2μm filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl.
Bio-activity : Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-50 ng/ml.
Molecular Mass : Approximately 11.4 kDa, a single, non-glycosylated polypeptide chain containing 99 amino acids.
Protein length : 99
AA Sequence : RVTKDAETEFMMSKLPLENPVLLDR FHATSADCCISYTPRSIPCSLLESY FETNSECSKPGVIFLTKKGRRFCAN PSDKQVQVCMRMLKLDTRIKTRKN
Endotoxin : Less than 1 EU/μg of rHuMIP-3/CCL23 as determined by LAL method.
Purity : >97% by SDS-PAGE and HPLC analysis.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions.
Gene Name : CCL23
Official Symbol : CCL23
Synonyms : CCL23; chemokine (C-C motif) ligand 23; SCYA23, small inducible cytokine subfamily A (Cys Cys), member 23; C-C motif chemokine 23; Ckb 8; CKb8; MIP 3; MPIF 1; hmrp-2a; C6 beta-chemokine; small-inducible cytokine A23; macrophage inflammatory protein 3; myeloid progenitor inhibitory factor 1; small inducible cytokine subfamily A (Cys-Cys), member 23; MIP3; Ckb-8; MIP-3; MPIF-1; SCYA23; Ckb-8-1; CK-BETA-8;
Gene ID : 6368
mRNA Refseq : NM_005064
Protein Refseq : NP_005055
MIM : 602494
UniProt ID : P55773

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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