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Recombinant Human CCNF Protein, GST-Tagged

Cat.No. : CCNF-0668H
Product Overview : Human CCNF full-length ORF (NP_001752.2, 1 a.a. - 786 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 114 kDa
AA Sequence : MGSGGVVHCRCAKCFCYPTKRRIRR RPRNLTILSLPEDVLFHILKWLSVE DILAVRAVHSQLKDLVDNHASVWAC ASFQELWPSPGNLKLFERAAEKGNF EAAVKLGIAYLYNEGLSVSDEARAE VNGLKASRFFSLAERLNVGAAPFIW LFIRPPWSVSGSCCKAVVHESLRAE CQLQRTHKASILHCLGRVLSLFEDE EKQQQAHDLFEEAAHQGCLTSSYLL WESDRRTDVSDPGRCLHSFRKLRDY AAKGCWEAQLSLAKACANANQLGLE VRASSEIVCQLFQASQAVSKQQVFS VQKGLNDTMRYILIDWLVEVATMKD FTSLCLHLTVECVDRYLRRRLVPRY RLQLLGIACMVICTRFISKEILTIR EAVWLTDNTYKYEDLVRMMGEIVSA LEGKIRVPTVVDYKEVLLTLVPVEL RTQHLCSFLCELSLLHTSLSAYAPA RLAAAALLLARLTHGQTQPWTTQLW DLTGFSYEDLIPCVLSLHKKCFHDD APKDYRQVSLTAVKQRFEDKRYGEI SQEEVLSYSQLCAALGVTQDSPDPP TFLSTGEIHAFLSSPSGRRTKRKRE NSLQEDRGSFVTTPTAELSSQEETL LGSFLDWSLDCCSGYEGDQESEGEK EGDVTAPSGILDVTVVYLNPEQHCC QESSDEEACPEDKGPQDPQALALDT QIPATPGPKPLVRTSREPGKDVTTS GYSSVSTASPTSSVDGGLGALPQPT SVLSLDSDSHTQPCHHQARKSCLQC RPPSPPESSVPQQQVKRINLCIHSE EEDMNLGLVRL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CCNF cyclin F [ Homo sapiens ]
Official Symbol : CCNF
Synonyms : CCNF; cyclin F; cyclin-F; FBX1; FBXO1; F-box only protein 1; G2/mitotic-specific cyclin-F;
Gene ID : 899
mRNA Refseq : NM_001761
Protein Refseq : NP_001752
MIM : 600227
UniProt ID : P41002

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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