Recombinant Human CCT5 Protein, GST-Tagged

• Cat.No.: CCT5-0714H
• Product Overview: Human CCT5 full-length ORF (AAH06543, 1 a.a. - 541 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM, Mar 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 85.25 kDa
• AA Sequence: MASMGTLAFDEYGRPFLIIKDQDRK SRLMGLEALKSHIMAAKAVANTMRT SLGPNGLDKMMVDKDGDVTVTNDGA TILSMMDVDHQIAKLMVELSKSQDD EIGDGTTGVVVLAGALLEEAEQLLD RGIHPIRIADGYEQAARVAIEHLDK ISDSVLVDIKDTEPLIQTAKTTLGS KVVNSCHRQMAEIAVNAVLTVADME RRDVDFELIKVEGKVGGRLEDTKLI KGVIVDKDFSHPQMPKKVEDAKIAI LTCPFEPPKPKTKHKLDVTSVEDYK ALQKYEKEKFEEMIQQIKETGANLA ICQWGFDDEANHLLLQNNLPAVRWV GGPEIELIAIATGGRIVPRFSELTA EKLGFAGLVQEISFGTTKDKMLVIE QCKNSRAVTIFIRGGNKMIIEEAKR SLHDALCVIRNLIRDNRVVYGGGAA EISCALAVSQEADKCPTLEQYAMRA FADALEVIPMALSENSGMNPIQTMT EVRARQVKEMNPALGIDCLHKGTND MKQQHVIETLIGKKQQISLATQMVR MILKIDDIRKPGESEE
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CCT5 chaperonin containing TCP1, subunit 5 (epsilon) [ Homo sapiens ]
• Official Symbol: CCT5
• Synonyms: CCT5; chaperonin containing TCP1, subunit 5 (epsilon); T-complex protein 1 subunit epsilon; KIAA0098; T-complex protein 1, epsilon subunit; CCTE; CCT-epsilon; TCP-1-epsilon
• Gene ID: 22948
• mRNA Refseq: NM_012073
• Protein Refseq: NP_036205
• MIM: 610150
• UniProt ID: P48643