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Recombinant Human CD200 Protein, Fc-tagged

Cat.No. : CD200-134H
Product Overview : Recombinant human CD200 protein with Fc tag was expressed in HEK293.
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Description : This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms.
Source : HEK293
Species : Human
Tag : Fc
Form : Lyophilized
Molecular Mass : 48.6 kDa
Protein length : 278
AA Sequence : MERLVIRMPFSHLSTYSLVWVMAAV VLCTAQVQVVTQDEREQLYTPASLK CSLQNAQEALIVTWQKKKAVSPENM VTFSENHGVVIQPAYKDKINITQLG LQNSTITFWNITLEDEGCYMCLFNT FGFGKISGTACLTVYVQPIVSLHYK FSEDHLNITCSATARPAPMVFWKVP RSGIENSTVTLSHPNGTTSVTSILH IKDPKNQVGKEVICQVLHLGTVTDF KQTVNKGYWFSVPLLLSIVSLVILL VLISILLYWKRHRNQDRGELSQGVQ KMT
Purity : > 98%
Applications : WB; ELISA; FACS; FC
Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
Storage : At -20 centigrade.
Concentration : 1 mg/mL
Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
Gene Name : CD200 CD200 molecule [ Homo sapiens (human) ]
Official Symbol : CD200
Synonyms : CD200; CD200 molecule; antigen identified by monoclonal MRC OX 2 , CD200 antigen , MOX1, MOX2; OX-2 membrane glycoprotein; MRC; OX 2; CD200 antigen; MRC OX-2 antigen; antigen identified by monoclonal MRC OX-2; MOX1; MOX2; OX-2;
Gene ID : 4345
mRNA Refseq : NM_001004196
Protein Refseq : NP_001004196
MIM : 155970
UniProt ID : P41217

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
08/01/2022

    Swift protein sequencing, helps identify unknown proteins.

    05/04/2022

      Great protein crystallization services, key for structural biology.

      05/02/2019

        Invaluable protein-protein interaction assays, integral for research.

        Q&As (7)

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        How does CD200 contribute to the regulation of bone marrow and hematopoietic stem cell niches? 10/04/2022

        CD200 regulates bone marrow and hematopoietic environments, supporting stem cell maintenance and differentiation.

        How does CD200 influence tumor immune evasion and the tumor microenvironment in cancer? 07/10/2021

        CD200 contributes to immune evasion in cancers, affecting tumor progression and response to immunotherapy.

        What role does CD200 play in the suppression of inflammatory responses in autoimmune diseases? 04/06/2021

        CD200 plays a role in suppressing inflammatory responses, which is crucial in autoimmune disease management.

        What are the effects of CD200 dysregulation on tissue graft rejection and transplant tolerance? 02/09/2019

        Dysregulation of CD200 affects tissue graft rejection, influencing transplant tolerance and success.

        How do alterations in CD200 expression impact the aging process and age-related immune changes? 09/17/2018

        Changes in CD200 expression impact the aging immune system, affecting age-related immune regulation and function.

        What is the impact of CD200 expression on neuroinflammatory processes and neurodegenerative diseases? 03/20/2018

        CD200 expression influences neuroinflammatory processes, potentially impacting neurodegenerative diseases.

        How does CD200 interact with its receptor CD200R, and what are the implications for immune regulation? 03/18/2018

        CD200 interacts with CD200R to modulate immune responses, promoting immune tolerance and reducing inflammation.

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