Recombinant Human CD24 protein, mFc-tagged, Biotinylated(Primary Amine Labeling)
Cat.No. : | CD24-5743H |
Product Overview : | Biotinylated Recombinant Human CD24 protein(P25063-1)(Ser27-Gly59)(Primary Amine Labeling), fused with C-terminal mFc tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | C-mFc |
Protein length : | Ser27-Gly59 |
Conjugation/Label : | Biotin; Primary Amine |
Form : | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization. |
Bio-activity : | Immobilized Anti-CD24 Antibody at 2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Human CD24, mFc Tag with the EC50 of 0.31μg/ml determined by ELISA. |
Molecular Mass : | The protein has a predicted MW of 29.5 kDa. Due to glycosylation, the protein migrates to 48-58 kDa based on Tris-Bis PAGE result. |
Endotoxin : | Less than 1EU per μg by the LAL method. |
Purity : | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Storage : | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Reconstitution : | Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Gene Name : | CD24 CD24 molecule [ Homo sapiens ] |
Official Symbol : | CD24 |
Synonyms : | CD24; CD24 molecule; CD24 antigen (small cell lung carcinoma cluster 4 antigen); signal transducer CD24; CD24A; FLJ22950; FLJ43543; MGC75043; |
Gene ID : | 100133941 |
mRNA Refseq : | NM_013230 |
Protein Refseq : | NP_037362 |
MIM : | 600074 |
UniProt ID : | P25063 |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewThe technician guided me through the process, which led to satisfactory results.
Prompt delivery helped me get satisfactory experimental results in a short period of time.
The protein composition was stable and concentrated, allowing me to obtain satisfactory experimental results.
Q&As (7)
Ask a questionOverexpression of CD24 increases the proliferation, migration and invasion of breast cancer cells.
CD24 has been closely associated with the study of diseases such as oral squamous cell carcinoma, breast cancer and gastric cancer.
CD24 expression was higher in breast cancer tissues compared to normal breast tissues.
CD24 is expressed on the surface of different cell types, including myeloid cells, keratinocytes, and macrophages.
Tumor growth was retarded after blocking CD24 expression.
CD24 regulates tumor cell growth and proliferation, metastasis and invasion by participating in relevant signal transduction pathways that mediate tumorigenesis and development.
CD24 binds to the inhibitory receptor Siglec-10.
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