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Recombinant Human CD24 protein, mFc-tagged, Biotinylated(Primary Amine Labeling)

Cat.No. : CD24-5743H
Product Overview : Biotinylated Recombinant Human CD24 protein(P25063-1)(Ser27-Gly59)(Primary Amine Labeling), fused with C-terminal mFc tag, was expressed in HEK293.
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Source : HEK293
Species : Human
Tag : C-mFc
Protein length : Ser27-Gly59
Conjugation/Label : Biotin; Primary Amine
Form : Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.
Bio-activity : Immobilized Anti-CD24 Antibody at 2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Human CD24, mFc Tag with the EC50 of 0.31μg/ml determined by ELISA.
Molecular Mass : The protein has a predicted MW of 29.5 kDa. Due to glycosylation, the protein migrates to 48-58 kDa based on Tris-Bis PAGE result.
Endotoxin : Less than 1EU per μg by the LAL method.
Purity : > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Storage : Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Reconstitution : Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Gene Name : CD24 CD24 molecule [ Homo sapiens ]
Official Symbol : CD24
Synonyms : CD24; CD24 molecule; CD24 antigen (small cell lung carcinoma cluster 4 antigen); signal transducer CD24; CD24A; FLJ22950; FLJ43543; MGC75043;
Gene ID : 100133941
mRNA Refseq : NM_013230
Protein Refseq : NP_037362
MIM : 600074
UniProt ID : P25063

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
10/31/2022

    The technician guided me through the process, which led to satisfactory results.

    10/18/2022

      Prompt delivery helped me get satisfactory experimental results in a short period of time.

      07/18/2021

        The protein composition was stable and concentrated, allowing me to obtain satisfactory experimental results.

        Q&As (7)

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        What are the effects of overexpressing CD24? 01/30/2023

        Overexpression of CD24 increases the proliferation, migration and invasion of breast cancer cells.

        What diseases is CD24 relevant to the study of? 08/16/2022

        CD24 has been closely associated with the study of diseases such as oral squamous cell carcinoma, breast cancer and gastric cancer.

        How do CD24 expression levels change in breast cancer tissues? 07/21/2022

        CD24 expression was higher in breast cancer tissues compared to normal breast tissues.

        Where is CD24 primarily expressed? 04/01/2022

        CD24 is expressed on the surface of different cell types, including myeloid cells, keratinocytes, and macrophages.

        What are the effects of blocking the expression of CD24? 02/04/2022

        Tumor growth was retarded after blocking CD24 expression.

        What biological processes is CD24 involved in? 11/04/2021

        CD24 regulates tumor cell growth and proliferation, metastasis and invasion by participating in relevant signal transduction pathways that mediate tumorigenesis and development.

        How is CD24 related to the inhibitory receptor Siglec-10? 03/11/2021

        CD24 binds to the inhibitory receptor Siglec-10.

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