Recombinant Human CD3D Protein, GST-Tagged

• Cat.No.: CD3D-0800H
• Product Overview: Human CD3D full-length ORF (NP_000723.1, 1 a.a. - 171 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 45.3 kDa
• AA Sequence: MEHSTFLSGLVLATLLSQVSPFKIP IEELEDRVFVNCNTSITWVEGTVGT LLSDITRLDLGKRILDPRGIYRCNG TDIYKDKESTVQVHYRMCQSCVELD PATVAGIIVTDVIATLLLALGVFCF AGHETGRLSGAADTQALLRNDQVYQ PLRDRDDAQYSHLGGNWARNK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CD3D CD3d molecule, delta (CD3-TCR complex) [ Homo sapiens ]
• Official Symbol: CD3D
• Synonyms: CD3D; CD3d molecule, delta (CD3-TCR complex); CD3d antigen, delta polypeptide (TiT3 complex), T3D; T-cell surface glycoprotein CD3 delta chain; CD3 delta; OKT3, delta chain; CD3 antigen, delta subunit; T-cell receptor T3 delta chain; CD3d antigen, delta polypeptide (TiT3 complex); T3D; CD3-DELTA
• Gene ID: 915
• mRNA Refseq: NM_000732
• Protein Refseq: NP_000723
• MIM: 186790
• UniProt ID: P04234