Recombinant Human CD3D&CD3E protein, Fc-Avi-tagged, Biotinylated
| Cat.No. : | CD3D&CD3E-234HB |
| Product Overview : | Biotinylated Human CD3 epsilon & CD3 delta Heterodimer Protein is expressed from mammalian with a Fc and Avi Tag at the C-terminal. It contains Asp 23-Asp 126 (CD3E) & Phe22-Ala105 (CD3D). |
- Specification
- Gene Information
- Related Products
| Description : | T-cell surface glycoprotein CD3 epsilon & CD3 delta chain, also known as CD3E & CD3D , are singlepass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Fc-Avi |
| Form : | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
| Molecular Mass : | The protein has a calculated MW of 40 kDa (CD3E) and 35.4 kDa(CD3D).As a result of glycosylation, the protein migrates to 48-60 kDa based on Bis-Tris PAGE result. |
| Protein length : | Asp 23-Asp 126 (CD3E) & Phe22-Ala105 (CD3D) |
| Endotoxin : | Less than 0.05EU per ug by the LAL method. |
| Purity : | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
| Gene Name : | CD3D&CD3E |
| Official Symbol : | CD3D&CD3E |
| Synonyms : | CD3; CD3D; CD3-DELTA; T3D; CD3E |
| Gene ID : | 915 & 916 |
| mRNA Refseq : | NM_000732.6 & NM_000733.4 |
| Protein Refseq : | NP_000723.1 & NP_000724.1 |
| MIM : | 186790 & 186830 |
| UniProt ID : | P04234 & P07766 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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