Recombinant Human CD3E(Gln22-Thr48) Protein, C-mFC-tagged

Cat.No. : CD3E-577H
Product Overview : Recombinant Human CD3E(P07766)(Gln22-Thr48) Protein, fused with a mFc tag at the C-terminus, was produced in HEK293.
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Source : HEK293
Species : Human
Tag : mFC
Form : Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Molecular Mass : The recombinant Human CD3E Protein has a predicted molecular mass of 28.5kDa , it migrates with an apparent molecular mass of 32-40kDa under reducing conditions
AA Sequence : Gln22-Thr48
Endotoxin : < 0.01 EU per μg of the protein as determined by the LAL method.
Purity : Greater than 95% as determined by reducing SDS-PAGE.
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 mg/ml. Centrifuge the vial at 4°C before opening to recover the entire contents.
Shipping : In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Protein length : Gln22-Thr48
Gene Name : CD3E CD3e molecule, epsilon (CD3-TCR complex) [ Homo sapiens ]
Official Symbol : CD3E
Synonyms : CD3E; CD3e molecule, epsilon (CD3-TCR complex); CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell antigen receptor complex, epsilon subunit of T3; T3E; TCRE; FLJ18683;
Gene ID : 916
mRNA Refseq : NM_000733
Protein Refseq : NP_000724
UniProt ID : P07766

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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03/22/2023

    Manufacturers with the capacity for bulk production can offer CD3E protein in larger quantities, which is advantageous for researchers working on large-scale experiments or collaborations.

    09/12/2021

      bulk production often leads to economies of scale, making the CD3E protein more cost-effective for research budgets.

      06/17/2018

        Manufacturers can actively seek collaborations and partnerships with researchers to develop new applications or optimize methodologies using CD3E protein.

        Q&As (5)

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        Can CD3E be used to assess the effectiveness of cancer immunotherapies? 04/07/2021

        Yes, CD3E levels and T-cell function can be monitored to evaluate the response to cancer immunotherapies like checkpoint inhibitors.

        Are there any CD3E-targeted therapies? 06/01/2017

        There are currently no approved therapies that directly target CD3E, but it is a target for research in developing immunotherapies and cancer treatments.

        Are there any ongoing clinical trials involving CD3E? 12/20/2016

        There may be ongoing clinical trials using CD3E-targeted therapies in the context of cancer and autoimmune diseases. It's important to check clinical trial databases for specific studies.

        Can CD3E levels be used to monitor the progression of HIV? 08/27/2016

        Yes, monitoring CD3E levels in HIV-infected individuals can provide valuable information about the progression of the disease and the effectiveness of antiretroviral therapy.

        How is CD3E used in allergy diagnostics? 06/22/2016

        CD3E can be used in research to study T-cell responses in allergic conditions, helping to better understand and diagnose allergies.

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