Recombinant Human CD3E&CD3G protein, Fc-Avi-tagged, Biotinylated

• Cat.No.: CD3E&CD3G-793HB
• Product Overview: Biotinylated Human CD3 epsilon & CD3 gamma Heterodimer Protein is expressed from mammalian with a Fc and Avi Tag at the C-terminal. It contains Asp 23-Asp 126(CD3E) & Gln 23-Ser 116(CD3G).

Specification

• Description: T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
• Source: HEK293
• Species: Human
• Tag: Fc-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a calculated MW of 40 kDa (CD3E) and 36.5 kDa (CD3G). As a result of glycosylation, the protein migrates to 75-90 kDa based on Bis-Tris PAGE result.
• Protein length: Asp 23-Asp 126(CD3E) & Gln 23-Ser 116(CD3G)
• Endotoxin: Less than 0.1EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: CD3E&CD3G
• Official Symbol: CD3E&CD3G
• Synonyms: CD3; CD3D; CD3-DELTA; T3D; CD3G
• Gene ID: 916 & 917
• mRNA Refseq: NM_000733.4 & NM_000073.3
• Protein Refseq: NP_000724.1 & NP_000064.1
• MIM: 186830 & 186740
• UniProt ID: P07766 & P09693