Recombinant Human CD58 protein, Fc-tagged
Cat.No. : | CD58-348H |
Product Overview : | Recombinant Human CD58 protein (Phe29-Arg215), fused to human IgG1 Fc tag at C-terminus, was expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58/LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis. |
Source : | HEK293 |
Species : | Human |
Tag : | human IgG1 Fc |
Form : | Lyophilized from 0.22 um filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 48.1 kDa. As a result of differtent glycosylation, the protein migrates as 60-75 kDa under reducing (R) condition, and 125-150 kDa under non-reducing (NR) condition (SDS-PAGE). |
Protein length : | 187 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | CD58 |
Official Symbol : | CD58 |
Synonyms : | ag3; LFA3; LFA-3 |
Gene ID : | 965 |
mRNA Refseq : | NM_001779.3 |
Protein Refseq : | NP_001770.1 |
MIM : | 153420 |
UniProt ID : | Q9BRW0 |
Products Types
◆ Recombinant Protein | ||
CD58-201H | Recombinant Human CD58 Protein, His-tagged | +Inquiry |
CD58-0835H | Recombinant Human CD58 Protein, GST-Tagged | +Inquiry |
CD58-165H | Recombinant Human CD58 Protein, His-tagged | +Inquiry |
CD58-246H | Recombinant Human CD58 Protein, His-tagged | +Inquiry |
CD58-166H | Recombinant Human CD58 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
CD58-797CCL | Recombinant Cynomolgus CD58 cell lysate | +Inquiry |
CD58-1127HCL | Recombinant Human CD58 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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