| Description : |
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Fc |
| Form : |
Lyophilized |
| Molecular Mass : |
59.2 kDa |
| Protein Length : |
354 |
| AA Sequence : |
MRLAVLFSGALLGLLAAQGTGNDCP HKKSATLLPSFTVTPTVTESTGTTS HRTTKSHKTTTHRTTTTGTTSHGPT TATHNPTTTSHGNVTVHPTSNSTAT SQGPSTATHSPATTSHGNATVHPTS NSTATSPGFTSSAHPEPPPPSPSPS PTSKETIGDYTWTNGSQPCVHLQAQ IQIRVMYTTQGGGEAWGISVLNPNK TKVQGSCEGAHPHLLLSFPYGHLSF GFMQDLQQKVVYLSYMAVEYNVSFP HAAQWTFSAQNASLRDLQAPLGQSF SCSNSSIILSPAVHLDLLSLRLQAA QLPHTGVFGQSFSCPSDRSILLPLI IGLILLGLLALVLIAFCIIRRRPSA YQAL |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
