"CD96" Related Products

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Recombinant Human CD96 Protein, T7-His-TEV-tagged

Cat.No.: CD96-25H
Product Overview: Full-length extracellular domain of human CD96 cDNA (22 – 519aa) was constructed with codon optimization gene synthesis and expressed with a human N-terminal T7-His-TEV cleavage site Tag (29aa) fusion. This protein was expressed in E. coli as inclusion bodies. The final product was refolded and chromatographically purified.
Description: The protein encoded by human T-cell surface protein tactile (CD96) gene is a receptor, which may be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. It promotes NK cell-target adhesion by interacting with PVR present on target cells. CD96 may function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation.
Source: E. coli
Species: Human
Tag : T7-His
Form: Liquid
AA Sequence: MASMTGGQQMGRGHHHHHHENLYFQGGEFVWEKTVNTEENVYATLGSDVNLTCQTQTVGFFVQMQWSKVTNKIDLIAVYHPQYGFYCAYGRPCESLVTFTETPENGSKWTLHLRNMSCSVSGRYECMLVLYPEGIQTKIYNLLIQTHVTADEWNSNHTIEIEINQTLEIPCFQNSSSKISSEFTYAWSVENSSTDSWVLLSKGIKEDNGTQETLISQNHLISNSTLLKDRVKLGTDYRLHLSPVQIFDDGRKFSCHIRVGPNKILRSSTTVKVFAKPEIPVIVENNSTDVLVERRFTCLLKNVFPKANITWFIDGSFLHDEKEGIYITNEERKGKDGFLELKSVLTRVHSNKPAQSDNLTIWCMALSPVPGNKVWNISSEKITFLLGSEISSTDPPLSVTESTLDTQPSPASSVSPARYPATSSVTLVDVSALRPNTTPQPSNSSMTTRGFNYPWTSSGTDTKKSVSRIPSETYSSSPSGAGSTLHDNVFTSTARAFSEVPTTANGSTKTNHVHITGIVVNKPKDGM
Purity: > 90% by SDS-PAGE.
Storage: Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 30 days.
Concentration: 0.2 mg/mL
Storage Buffer: Sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, Sucrose and DTT.
Gene Name: CD96
Official Symbol: CD96 CD96 molecule [ Homo sapiens (human) ]
Synonyms: CD96; CD96 molecule; TACTILE; T-cell surface protein tactile; T cell activation, increased late expression; cell surface antigen CD96; t cell-activated increased late expression protein
Gene ID: 10225
mRNA Refseq: NM_005816
Protein Refseq: NP_005807
MIM: 606037
UniProt ID: P40200

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