"CD96" Related Products

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Recombinant Human CD96 Protein, T7-His-TEV-tagged

Cat.No. : CD96-25H
Product Overview : Full-length extracellular domain of human CD96 cDNA (22 – 519aa) was constructed with codon optimization gene synthesis and expressed with a human N-terminal T7-His-TEV cleavage site Tag (29aa) fusion. This protein was expressed in E. coli as inclusion bodies. The final product was refolded and chromatographically purified.
Description : The protein encoded by human T-cell surface protein tactile (CD96) gene is a receptor, which may be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. It promotes NK cell-target adhesion by interacting with PVR present on target cells. CD96 may function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation.
Source : E. coli
Species : Human
Tag : T7-His
Form : Liquid
AA Sequence : MASMTGGQQMGRGHHHHHHENLYFQGGEFVWEKTVNTEENVYATLGSDVNLTCQTQTVGFFVQMQWSKVTNKIDLIAVYHPQYGFYCAYGRPCESLVTFTETPENGSKWTLHLRNMSCSVSGRYECMLVLYPEGIQTKIYNLLIQTHVTADEWNSNHTIEIEINQTLEIPCFQNSSSKISSEFTYAWSVENSSTDSWVLLSKGIKEDNGTQETLISQNHLISNSTLLKDRVKLGTDYRLHLSPVQIFDDGRKFSCHIRVGPNKILRSSTTVKVFAKPEIPVIVENNSTDVLVERRFTCLLKNVFPKANITWFIDGSFLHDEKEGIYITNEERKGKDGFLELKSVLTRVHSNKPAQSDNLTIWCMALSPVPGNKVWNISSEKITFLLGSEISSTDPPLSVTESTLDTQPSPASSVSPARYPATSSVTLVDVSALRPNTTPQPSNSSMTTRGFNYPWTSSGTDTKKSVSRIPSETYSSSPSGAGSTLHDNVFTSTARAFSEVPTTANGSTKTNHVHITGIVVNKPKDGM
Purity : > 90% by SDS-PAGE.
Storage : Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 30 days.
Concentration : 0.2 mg/mL
Storage Buffer : Sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, Sucrose and DTT.
Gene Name : CD96
Official Symbol : CD96 CD96 molecule [ Homo sapiens (human) ]
Synonyms : CD96; CD96 molecule; TACTILE; T-cell surface protein tactile; T cell activation, increased late expression; cell surface antigen CD96; t cell-activated increased late expression protein
Gene ID : 10225
mRNA Refseq : NM_005816
Protein Refseq : NP_005807
MIM : 606037
UniProt ID : P40200

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