Recombinant Human CD97 Protein, GST-Tagged

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Recombinant Human CD97 Protein, GST-Tagged

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Cat.No. : CD97-0889H
Product Overview : Human CD97 full-length ORF (AAH26690, 1 a.a. - 742 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 107.36 kDa
AA Sequence : MGGRVFLAFCVWLTL PGAETQDSRGCARWC PQNSSCVNATACRCN PGFSSFSEIITTPTE TCDDINECATPSKVS CGKFSDCWNTEGSYD CVCSPGYEPVSGAKT FKNESENTCQDVDEC SSGRHQCDSSTVCFN TVGSYSCRCRPGWKP RHGIPNNQKDTVCED MTFSTWTPPPGVHSQ TLSRFFDKVQDLGRD SKTSSAEVTIQNVIK LVDELMEAPGDVEAL APPVRHLIATQLLSN LEDIMRILAKSLPKG PFTYISPSNTELTLM IQERGDKNVTMGQSS ARMKLNWAVAAGAED PGPAVAGILSIQNMT TLLANASLNLHSKKQ AELEEIYESSIRGVQ LRRLSAVNSIFLSHN NTKELNSPILFAFSH LESSDGEAGRDPPAK DVMPGPRQELLCAFW KSDSDRGGHWATEGC QVLGSKNGSTTCQCS HLSSFAILMAHYDVE DWKLTLITRVGLALS LFCLLLCILTFLLVR PIQGSRTTIHLHLCI CLFVGSTIFLAGIEN EGGQVGLRCRLVAGL LHYCFLAAFCWMSLE GLELYFLVVRVFQGQ GLSTRWLCLIGYGVP LLIVGVSAAIYSKGY GRPRYCWLDFEQGFL WSFLGPVTFIILCNA VIFVTTVWKLTQKFS EINPDMKKLKKARAL TITAIAQLFLLGCTW VFGLFIFDDRSLVLT YVFTILNCLQGAFLY LLHCLLNKKVREEYR KWACLVAGGSKYSEF TSTTSGTGHNQTRAL RASESGI
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CD97 CD97 molecule [ Homo sapiens ]
Official Symbol : CD97
Synonyms : CD97; CD97 molecule; CD97 antigen; leukocyte antigen CD97; seven transmembrane helix receptor; seven span transmembrane protein; seven transmembrane; heterodimeric receptor associated with inflammation; TM7LN1; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation;
Gene ID : 976
mRNA Refseq : NM_001025160
Protein Refseq : NP_001020331
MIM : 601211
UniProt ID : P48960

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