Recombinant Human CDC42EP3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CDC42EP3-4687H
• Product Overview: CDC42EP3 MS Standard C13 and N15-labeled recombinant protein (NP_006440) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 27.7 kDa
• AA Sequence: MPAKTPIYLKAANNKKGKKFKLRDI LSPDMISPPLGDFRHTIHIGKEGQH DVFGDISFLQGNYELLPGNQEKAHL GQFPGHNEFFRANSTSDSVFTETPS PVLKNAISLPTIGGSQALMLPLLSP VTFNSKQESFGPAKLPRLSCEPVME EKAQEKSSLLENGTVHQGDTSWGSS GSASQSSQGRDSHSSSLSEQYPDWP AEDMFDHPTPCELIKGKTKSEESLS DLTGSLLSLQLDLGPSLLDEVLNVM DKNKTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CDC42EP3 CDC42 effector protein 3 [ Homo sapiens (human) ]
• Official Symbol: CDC42EP3
• Synonyms: CDC42EP3; CDC42 effector protein 3; UB1; CEP3; BORG2; cdc42 effector protein 3; CDC42 effector protein (Rho GTPase binding) 3; CRIB-containing BORG2 protein; MSE55-related Cdc42-binding protein; MSE55-related protein; binder of Rho GTPases 2
• Gene ID: 10602
• mRNA Refseq: NM_006449
• Protein Refseq: NP_006440
• MIM: 606133
• UniProt ID: Q9UKI2