Recombinant Human CDH16 Protein, GST-Tagged

• Cat.No.: CDH16-0976H
• Product Overview: Human CDH16 full-length ORF (NP_004053.1, 1 a.a. - 829 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 116.3 kDa
• AA Sequence: MVPAWLWLLCVSVPQALPKAQPAEL SVEVPENYGGNFPLYLTKLPLPREG AEGQIVLSGDSGKATEGPFAMDPDS GFLLVTRALDREEQAEYQLQVTLEM QDGHVLWGPQPVLVHVKDENDQVPH FSQAIYRARLSRGTRPGIPFLFLEA SDRDEPGTANSDLRFHILSQAPAQP SPDMFQLEPRLGALALSPKGSTSLD HALERTYQLLVQVKDMGDQASGHQA TATVEVSIIESTWVSLEPIHLAENL KVLYPHHMAQVHWSGGDVHYHLESH PPGPFEVNAEGNLYVTRELDREAQA EYLLQVRAQNSHGEDYAAPLELHVL VMDENDNVPICPPRDPTVSIPELSP PGTEVTRLSAEDADAPGSPNSHVVY QLLSPEPEDGVEGRAFQVDPTSGSV TLGVLPLRAGQNILLLVLAMDLAGA EGGFSSTCEVEVAVTDINDHAPEFI TSQIGPISLPEDVEPGTLVAMLTAI DADLEPAFRLMDFAIERGDTEGTFG LDWEPDSGHVRLRLCKNLSYEAAPS HEVVVVVQSVAKLVGPGPGPGATAT VTVLVERVMPPPKLDQESYEASVPI SAPAGSFLLTIQPSDPISRTLRFSL VNDSEGWLCIEKFSGEVHTAQSLQG AQPGDTYTVLVEAQDTDEPRLSASA PLVIHFLKAPPAPALTLAPVPSQYL CTPRQDHGLIVSGPSKDPDLASGHG PYSFTLGPNPTVQRDWRLQTLNGSH AYLTLALHWVEPREHIIPVVVSHNA QMWQLLVRVIVCRCNVEGQCMRKVG RMKGMPTKLSAVGILVGTLVAIGIF LILIFTHWTMSRKKDPDQPADSVPL KATV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CDH16 cadherin 16, KSP-cadherin [ Homo sapiens ]
• Official Symbol: CDH16
• Synonyms: CDH16; cadherin 16, KSP-cadherin; cadherin-16; KSP-cadherin; kidney-specific cadherin
• Gene ID: 1014
• mRNA Refseq: NM_001204744
• Protein Refseq: NP_001191673
• MIM: 603118
• UniProt ID: O75309