Recombinant Human CDK13/Cyclin K protein, GST-tagged

• Cat.No.: CDK13-01H
• Product Overview: Recombinant human CDK13 (516-end) /Cyclin K complex was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag on both proteins.

Specification

• Description: CDK13 or cyclin-dependent kinase 13 is a member of the cyclin-dependent serine/threonine protein kinase family which are well known for their essential roles as master switches in cell cycle control. CDK13 forms a complex with cyclin K and is predicted to play a role in gene regulation. CDK13 may play a role in mRNA processing and is thought to be involved in regulation of hematopoiesis. The CYCK-CDK12 and CYCK-CDK13 complexes display unique function in cell cycle and gene regulation.
• Source: Insect cells
• Species: Human
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: CDK13 ~160 kDa and Cyclin K ~67 kDa
• Protein length: CDK13 (516-end) and Cyclin K (Full Length)
• Purity: >70%
• Applications: Western Blot
• Stability: 1 year at -70 centigrade from date of shipment
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 ug/uL

Gene Information

• Gene Name: CDK13 cyclin-dependent kinase 13 [ Homo sapiens ]
• Official Symbol: CDK13
• Synonyms: CDK13; cyclin-dependent kinase 13; CDC2L5, cell division cycle 2 like 5 (cholinesterase related cell division controller); CDC2L; CHED; cholinesterase related cell division controller; KIAA1791; CDC2-related protein kinase 5; cell division protein kinase 13; cell division cycle 2-like protein kinase 5; cholinesterase-related cell division controller; CDC2L5; hCDK13; FLJ35215
• Gene ID: 8621
• mRNA Refseq: NM_003718
• Protein Refseq: NP_003709
• MIM: 603309
• UniProt ID: Q14004
• Chromosome Location: 7p14.1
• Function: ATP binding; RNA polymerase II carboxy-terminal domain kinase activity; cyclin binding; cyclin-dependent protein kinase activity; nucleotide binding; protein binding; protein kinase activity