Recombinant Human CDKL3, GST-tagged

• Cat.No.: CDKL3-11059H
• Product Overview: Recombinant Human CDKL3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-279a.a.
• Description: The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Two transcript variants encoding different isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CDKL3 cyclin-dependent kinase-like 3 [ Homo sapiens ]
• Official Symbol: CDKL3
• Synonyms: CDKL3; cyclin-dependent kinase-like 3; NKIAMRE; serine threonine protein kinase NKIAMRE; serine-threonine protein kinase NKIAMRE; serine/threonine-protein kinase NKIAMRE
• Gene ID: 51265
• mRNA Refseq: NM_001113575
• Protein Refseq: NP_001107047
• MIM: 608459
• UniProt ID: Q8IVW4
• Chromosome Location: 5q31
• Function: ATP binding; cyclin-dependent protein kinase activity; nucleotide binding; protein kinase activity