Recombinant Human CDKN2AIP Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CDKN2AIP-2836H
• Product Overview: CDKN2AIP MS Standard C13 and N15-labeled recombinant protein (NP_060102) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is critical to the DNA damage response. Two transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 61.1 kDa
• AA Sequence: MAQEVSEYLSQNPRVAAWVEALRCD GETDKHWRHRRDFLLRNAGDLAPAG GAASASTDEAADAESGTRNRQLQQL ISFSMAWANHVFLGCRYPQKVMDKI LSMAEGIKVTDAPTYTTRDELVAKV KKRGISSSNEGVEEPSKKRVIEGKN SSAVEQDHAKTSAKTERASAQQENS STCIGSAIKSESGNSARSSGISSQN SSTSDGDRSVSSQSSSSVSSQVTTA GSGKASEAEAPDKHGSSFVSLLKSS VNSHMTQSTDSRQQSGSPKKSALEG SSASASQSSSEIEVPLLGSSGSSEV ELPLLSSKPSSETASSGLTSKTSSE ASVSSSVAKNSSSSGTSLLTPKSSS STNTSLLTSKSTSQVAASLLASKSS SQTSGSLVSKSTSLASVSQLASKSS SQTSTSQLPSKSTSQSSESSVKFSC KLTNEDVKQKQPFFNRLYKTVAWKL VAVGGFSPNVNHGELLNAAIEALKA TLDVFFVPLKELADLPQNKSSQESI VCELRCKSVYLGTGCGKSKENAKAV ASREALKLFLKKKVVVKICKRKYRG SEIEDLVLLDEESRPVNLPPALKHP QELLTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CDKN2AIP CDKN2A interacting protein [ Homo sapiens (human) ]
• Official Symbol: CDKN2AIP
• Synonyms: CDKN2AIP; CDKN2A interacting protein; CDKN2A-interacting protein; CARF; collaborates/cooperates with ARF (alternate reading frame) protein; FLJ20036; collaborator of ARF
• Gene ID: 55602
• mRNA Refseq: NM_017632
• Protein Refseq: NP_060102
• MIM: 615914
• UniProt ID: Q9NXV6