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Recombinant Human CEACAM1 Protein

Cat.No. : CEACAM1-1090H
Product Overview : Human CEACAM1 full-length ORF (NP_001020083.1) recombinant protein without tag.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. [provided by RefSeq, May 2010]
Source : Wheat Germ
Species : Human
Form : Liquid
Molecular Mass : 50.5 kDa
AA Sequence : MGHLSAPLHRVRVPWQGLLLTASLL TFWNPPTTAQLTTESMPFNVAEGKE VLLLVHNLPQQLFGYSWYKGERVDG NRQIVGYAIGTQQATPGPANSGRET IYPNASLLIQNVTQNDTGFYTLQVI KSDLVNEEATGQFHVYPELPKPSIS SNNSNPVEDKDAVAFTCEPETQDTT YLWWINNQSLPVSPRLQLSNGNRTL TLLSVTRNDTGPYECEIQNPVSANR SDPVTLNVTYGPDTPTISPSDTYYR PGANLSLSCYAASNPPAQYSWLING TFQQSTQELFIPNITVNNSGSYTCH ANNSVTGCNRTTVKTIIVTELSPVV AKPQIKASKTTVTGDKDSVNLTCST NDTGISIRWFFKNQSLPSSERMKLS QGNTTLSINPVKREDAGTYWCEVFN PISKNQSDPIMLNVNYNALPQENGL SPGAIAGIVIGVVALVALIAVALAC FLHFGKTGSSGPLQ
Applications : Antibody Production
Functional Study
Compound Screening
Usage : Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 25 mM Tris-HCl of pH8.0 containing 2% glycerol.
Gene Name : CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) [ Homo sapiens ]
Official Symbol : CEACAM1
Synonyms : CEACAM1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); BGP; carcinoembryonic antigen-related cell adhesion molecule 1; BGP1; CD66a; antigen CD66; CD66a antigen; BGPI;
Gene ID : 634
mRNA Refseq : NM_001024912
Protein Refseq : NP_001020083
MIM : 109770
UniProt ID : P13688

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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