Recombinant human CENPQ, His-tagged

• Cat.No.: CENPQ-2481H
• Product Overview: Recombinant human CENPQ protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: CENPQ is a subunit of a CENPH-CENPI-associated centromeric complex that targets CENPA to centromeres and is required for proper kinetochore function and mitotic progression.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
• Molecular Mass: 33.0kDa (291aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSGKANA SKKNAQQLKR NPKRKKDNEE VVLSENKVRN TVKKNKNHLK DLSSEGQTKH TNLKHGKTAA SKRKTWQPLS KSTRDHLQTM MESVIMTILS NSIKEKEEIQ YHLNFLKKRL LQQCETLKVP PKKMEDLTNV SSLLNMERAR DKANEEGLAL LQEEIDKMVE TTELMTGNIQ SLKNKIQILA SEVEEEEERV KQMHQINSSG VLSLPELSQK TLKAPTLQKE ILALIPNQNA LLKDLDILHN SSQMKSMSTF IEEAYKKLDA S
• Purity: >85 % by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: CENPQ centromere protein Q [ Homo sapiens ]
• Official Symbol: CENPQ
• Synonyms: CENPQ; centromere protein Q; C6orf139, chromosome 6 open reading frame 139; CENP Q; FLJ10545; CENP-Q; C6orf139
• Gene ID: 55166
• mRNA Refseq: NM_018132
• Protein Refseq: NP_060602
• MIM: 611506
• UniProt ID: Q7L2Z9
• Chromosome Location: 6p12.3
• Pathway: Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; DNA Replication, organism-specific biosystem; Deposition of New CENPA-containing Nucleosomes at the Centromere, organism-specific biosystem; M Phase, organism-specific biosystem; Mitotic M-M/G1 phases, organism-specific biosystem