Recombinant Human CFL1 Protein, GST-Tagged

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Recombinant Human CFL1 Protein, GST-Tagged

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Cat.No. : CFL1-1172H
Product Overview : Human CFL1 full-length ORF (AAH11005, 1 a.a. - 166 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 44 kDa
AA Sequence : MASGVAVSDG VIKVFNDMKV RKSSTPEEVK KRKKAVLFCL SEDKKNIILE EGKEILVGDV GQTVDDPYAT FAKMLPDKDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS KDAIKKKLTG IKHELQANCY EGVKDRCTLA EKLGGSAVIS LEGKPL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CFL1 cofilin 1 (non-muscle) [ Homo sapiens ]
Official Symbol : CFL1
Synonyms : CFL1; cofilin 1 (non-muscle); CFL; cofilin-1; p18; 18 kDa phosphoprotein; cofilin, non-muscle isoform;
Gene ID : 1072
mRNA Refseq : NM_005507
Protein Refseq : NP_005498
MIM : 601442
UniProt ID : P23528

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