Recombinant Human Cofilin 1 (non-muscle), His-tagged
| Cat.No. : | CFL1-1580H |
| Product Overview : | Recombinant full-length human CFL1 was expressed in E. coli cells using an N-terminal His tag. |
- Specification
- Gene Information
- Related Products
| Cat. No. : | CFL1-1580H |
| Description : | Cofilin 1 (non-muscle), also known as CFL1, is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. CFL1 processed proteins are most probably produced by HIV-1 protease digestion. |
| Applications : | Western Blot |
| Molecular Weight : | 23 kDa |
| Expression System : | E. coli |
| Species : | Human |
| Form : | Recombinant protein stored in 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 2 mM DTT, 25 % glycerol. |
| Purity : | > 95 % |
| Concentration : | 0.2 ug/ul |
| Sequences : | Full-length |
| Storage : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
| Pathways : | Axon guidance; CDC42 signaling events; CXCR4-mediated signaling events; Fc gamma R-mediated phagocytosis; Formation of Platelet plug; G13 Signaling Pathway; Hemostasis; Pertussis; Platelet Activation; RAC1 signaling pathway; Regulation of Actin Cytoskeleton; RhoA signaling pathway; Sema3A PAK dependent Axon repulsion; Semaphorin interactions |
| Gene Name : | CFL1 cofilin 1 (non-muscle) [ Homo sapiens ] |
| Official Symbol : | CFL1 |
| Synonyms : | CFL1; cofilin 1 (non-muscle); CFL; cofilin-1; p18; OTTHUMP00000233679; OTTHUMP00000233680; OTTHUMP00000233681; OTTHUMP00000233682; OTTHUMP00000233740; OTTHUMP00000233741; OTTHUMP00000233742; 18 kDa phosphoprotein; Cofilin-1, non-muscle isoform; Cofilin-1 |
| Gene ID : | 1072 |
| mRNA Refseq : | NM_005507 |
| Protein Refseq : | NP_005498 |
| MIM : | 601442 |
| UniProt ID : | P23528 |
| Chromosome Location : | 11q13 |
| Function : | actin binding; protein binding |
Products Types
| ◆ Recombinant Protein | ||
| CFL1-0152H | Recombinant Human CFL1 Protein (M1-L166), His/Step tagged | +Inquiry |
| Cfl1-870M | Recombinant Mouse Cfl1 Protein, GST-tagged | +Inquiry |
| CFL1-1014R | Recombinant Rat CFL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
| CFL1-768H | Recombinant Human CFL1 Protein, His-tagged | +Inquiry |
| CFL1-1172H | Recombinant Human CFL1 Protein, GST-Tagged | +Inquiry |
| ◆ Lysates | ||
| CFL1-7555HCL | Recombinant Human CFL1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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