Recombinant Human CGAS Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CGAS-6581H
• Product Overview: C6orf150 MS Standard C13 and N15-labeled recombinant protein (NP_612450) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: CGAS (Cyclic GMP-AMP Synthase) is a Protein Coding gene. Diseases associated with CGAS include Herpes Simplex and Sting-Associated Vasculopathy With Onset In Infancy. Among its related pathways are Shigellosis and Cytosolic sensors of pathogen-associated DNA. An important paralog of this gene is ITPRIPL2.
• Molecular Mass: 58.9 kDa
• AA Sequence: MQPWHGKAMQRASEAGATAPKASARNARGAPMDPNESPAAPEAALPKAGKFGPARKSGSRQKKSAPDTQERPPVRATGARAKKAPQRAQDTQPSDATSAPGAEGLEPPAAREPALSRAGSCRQRGARCSTKPRPPPGPWDVPSPGLPVSAPILVRRDAAPGASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRNPKENHLSQFLEGEILSASKMLSKFRKIIKEEINDIKDTDVIMKRKRGGSPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAKEGNGFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFDEFTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CGAS cyclic GMP-AMP synthase [ Homo sapiens (human) ]
• Official Symbol: CGAS
• Synonyms: CGAS; cyclic GMP-AMP synthase; MB21D1; h-cGAS; C6orf150; cyclic GMP-AMP synthase; 2'3'-cGAMP synthase; Mab-21 domain containing 1; cGAMP synthase; mab-21 domain-containing protein 1; protein MB21D1; EC 2.7.7.86
• Gene ID: 115004
• mRNA Refseq: NM_138441
• Protein Refseq: NP_612450
• MIM: 613973
• UniProt ID: Q8N884