Recombinant Human CHCHD3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CHCHD3-582H
• Product Overview: CHCHD3 MS Standard C13 and N15-labeled recombinant protein (NP_060282) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is an inner mitochondrial membrane scaffold protein. Absence of the encoded protein affects the structural integrity of mitochondrial cristae and leads to reductions in ATP production, cell growth, and oxygen consumption. This protein is part of the mitochondrial contact site and cristae organizing system (MICOS). Several transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 26.2 kDa
• AA Sequence: MGGTTSTRRVTFEADENENITVVKG IRLSENVIDRMKESSPSGSKSQRYS GAYGASVSDEELKRRVAEELALEQA KKESEDQKRLKQAKELDRERAAANE QLTRAILRERICSEEERAKAKHLAR QLEEKDRVLKKQDAFYKEQLARLEE RSSEFYRVTTEQYQKAAEEVEAKFK RYESHPVCADLQAKILQCYRENTHQ TLKCSALATQYMHCVNHAKQSMLEK GGTRTRPLEQKLISEEDLAANDILD YKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 [ Homo sapiens (human) ]
• Official Symbol: CHCHD3
• Synonyms: CHCHD3; coiled-coil-helix-coiled-coil-helix domain containing 3; coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial; FLJ20420; MINOS3; mitochondrial inner membrane organizing system 3; PPP1R22; protein phosphatase 1; regulatory subunit 22; protein phosphatase 1, regulatory subunit 22
• Gene ID: 54927
• mRNA Refseq: NM_017812
• Protein Refseq: NP_060282
• MIM: 613748
• UniProt ID: Q9NX63