Recombinant Human CHI3L2 Protein, His-tagged

• Cat.No.: CHI3L2-30H
• Product Overview: Recombinant human CHI3L2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Description: CHI3L2, also known as chitinase-3-like protein 2, belongs to chitinase protein family. It is secreted by synovial fibroblasts, chondrocytes, and TGFb/IL4 stimulated monocyte derived macrophages. It has been proposed as a potential biomarker for osteoarthritis.
• Source: Insect cell
• Species: Human
• Tag: His
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 41.9kDa (372aa)40-57KDa (SDS–PAGE under reducing conditions)
• AA Sequence: YKLVCYFTNW SQDRQEPGKF TPENIDPFLC SHLIYSFASI ENNKVIIKDK SEVMLYQTIN SLKTKNPKLK ILLSIGGYLF GSKGFHPMVDSSTSRLEFIN SIILFLRNHN FDGLDVSWIY PDQKENTHFT VLIHELAEAF QKDFTKSTKE RLLLTAGVSA GRQMIDNSYQ VEKLAKDLDFINLLSFDFHG SWEKPLITGH NSPLSKGWQD RGPSSYYNVE YAVGYWIHKG MPSEKVVMGI PTYGHSFTLA SAETTVGAPA SGPGAAGPITESSGFLAYYE ICQFLKGAKI TRLQDQQVPY AVKGNQWVGY DDVKSMETKV QFLKNLNLGG AMIWSIDMDD FTGKSCNQGP YPLVQAVKRSLGSLLEHHHH HH
• Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Purity: >90% by SDS – PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: CHI3L2 chitinase 3-like 2 [ Homo sapiens ]
• Official Symbol: CHI3L2
• Synonyms: CHI3L2; chitinase 3-like 2; chitinase-3-like protein 2; YKL 39; YKL39; chondrocyte protein 39; YKL-39
• Gene ID: 1117
• mRNA Refseq: NM_001025197
• Protein Refseq: NP_001020368
• MIM: 601526
• UniProt ID: Q15782
• Chromosome Location: 1p13.3
• Function: cation binding; chitinase activity; hydrolase activity