Recombinant Human CHML Protein, GST-Tagged

• Cat.No.: CHML-1245H
• Product Overview: Human CHML full-length ORF (NP_001812.2, 1 a.a. - 656 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina. CHML is localized close to the gene for Usher syndrome type II. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 100.5 kDa
• AA Sequence: MADNLPTEFDVVIIGTGLPESILAA ACSRSGQRVLHIDSRSYYGGNWASF SFSGLLSWLKEYQQNNDIGEESTVV WQDLIHETEEAITLRKKDETIQHTE AFCYASQDMEDNVEEIGALQKNPSL GVSNTFTEVLDSALPEESQLSYFNS DEMPAKHTQKSDTEISLEVTDVEES VEKEKYCGDKTCMHTVSDKDGDKDE SKSTVEDKADEPIRNRITYSQIVKE GRRFNIDLVSKLLYSQGLLIDLLIK SDVSRYVEFKNVTRILAFREGKVEQ VPCSRADVFNSKELTMVEKRMLMKF LTFCLEYEQHPDEYQAFRQCSFSEY LKTKKLTPNLQHFVLHSIAMTSESS CTTIDGLNATKNFLQCLGRFGNTPF LFPLYGQGEIPQGFCRMCAVFGGIY CLRHKVQCFVVDKESGRCKAIIDHF GQRINAKYFIVEDSYLSEETCSNVQ YKQISRAVLITDQSILKTDLDQQTS ILIVPPAEPGACAVRVTELCSSTMT CMKDTYLVHLTCSSSKTAREDLESV VKKLFTPYTETEINEEELTKPRLLW ALYFNMRDSSGISRSSYNGLPSNVY VCSGPDCGLGNEHAVKQAETLFQEI FPTEEFCPPPPNPEDIIFDGDDKQP EAPGTNNVVMAKLESSEESKNLESP EKHLQN
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CHML choroideremia-like (Rab escort protein 2) [ Homo sapiens ]
• Official Symbol: CHML
• Synonyms: CHML; choroideremia-like (Rab escort protein 2); rab proteins geranylgeranyltransferase component A 2; REP 2; choroideraemia-like protein; REP2; FLJ10071; FLJ13361
• Gene ID: 1122
• mRNA Refseq: NM_001821
• Protein Refseq: NP_001812
• MIM: 118825
• UniProt ID: P26374