Recombinant Human CKMT1A Protein (Ser41-Ile250), His tagged

• Cat.No.: CKMT1A-2155H
• Product Overview: Recombinant human CKMT1A (Ser41-Ile250) fused with His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Ser41-Ile250
• Description: CKMT1A belongs to the ATP: guanido phosphotransferase family. It contains 1 phosphagen kinase C-terminal domain and 1 phosphagen kinase N-terminal domain. CKMT1A gene is one of two genes which encode the ubiquitous mitochondrial creatine kinase (CKMT1). CKMT1 is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK (CKMT2) and ubiquitous MtCK, encoded by separate genes. CKMT1 occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Ubiquitous mitochondrial creatine kinase has 8% homology with the coding exons of sarcomeric CKMT1.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 25.15 kDa
• Purity: >90% as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: CKMT1A creatine kinase, mitochondrial 1A [ Homo sapiens (human) ]
• Official Symbol: CKMT1A
• Synonyms: CKMT1A; creatine kinase, mitochondrial 1A; CKMT1, creatine kinase, mitochondrial 1 (ubiquitous); creatine kinase U-type, mitochondrial; U-MtCK; mia-CK; ubiquitous mitochondrial creatine kinase; acidic-type mitochondrial creatine kinase; creatine kinase, mitochondrial 1 (ubiquitous); CKMT1; UMTCK; CKMT1B; FLJ50967
• Gene ID: 548596
• mRNA Refseq: NM_001015001
• Protein Refseq: NP_001015001
• MIM: 613415
• UniProt ID: P12532