Recombinant Human Clathrin, Light Chain B, His-tagged

• Cat.No.: CLTB-3044H
• Product Overview: Recombinant Human CLTB was produced inE.coliwith a His tag at N-terminus. MW = 25190 Da (1-211 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-211 a.a.
• Description: Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants.
• Form: 10 mM Tris. pH 8.0. 0.002% NaN3. 3mM NaCl. 2.5mM Imidazole.
• Purity: 95%.
• Applications: MS. SDS.

Gene Information

• Gene Name: CLTB clathrin, light chain B [ Homo sapiens ]
• Synonyms: CLTB; clathrin, light chain B; LCB; clathrin light chain B; clathrin, light chain (Lcb); clathrin, light polypeptide (Lcb)
• Gene ID: 1212
• mRNA Refseq: NM_001834
• Protein Refseq: NP_001825
• MIM: 118970
• UniProt ID: P09497
• Chromosome Location: 4q2-q3; 5q35
• Pathway: Bacterial invasion of epithelial cells; Endocytosis; Huntington"s disease; Lysosome
• Function: peptide binding; protein binding; structural molecule activity