"CLCA1" Related Products

Recombinant Human CLCA1 protein, His-tagged

Cat.No.: CLCA1-01H
Product Overview: Recombinant Human CLCA1(a.a. 22-695) fused with His tag was expressed in E. coli.
Description: This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine.
Source: E. coli
Species: Human
Tag: His
Form: PBS buffer (pH 7.4).
Purity: > 95% determined by SDS-PAGE.
Storage: For short term, storage it at +4 centigrade, For long term storage, prepare aliquots with 20% glycerol and store at -20 centigrade. Avoid freeze/thaw cycles.
Concentration: 0.31 mg/ml
Gene Name: CLCA1 chloride channel accessory 1 [ Homo sapiens ]
Official Symbol: CLCA1
Synonyms: CLCA1; chloride channel accessory 1; chloride channel regulator 1 , chloride channel, calcium activated, family member 1; calcium-activated chloride channel regulator 1; CaCC; CLCRG1; chloride channel regulator 1; calcium-dependent chloride channel-1; calcium-activated chloride channel protein 1; CLCA family member 1, chloride channel regulator; calcium-activated chloride channel family member 1; chloride channel, calcium activated, family member 1; CACC; GOB5; CACC1; CaCC-1; hCLCA1; hCaCC-1; FLJ95147;
Gene ID: 1179
mRNA Refseq: NM_001285
Protein Refseq: NP_001276
MIM: 603906
UniProt ID: A8K7I4
Chromosome Location: 1p22.3
Pathway: Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Olfactory transduction, organism-specific biosystem; Olfactory transduction, conserved biosystem; Pancreatic secretion, organism-specific biosystem; Pancreatic secretion, conserved biosystem;
Function: chloride channel activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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