Description : |
The protein encoded by this gene belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was found to associate with both microtubules and an organelle called the dendritic lamellar body. This gene is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
115.6 kDa |
AA Sequence : |
MQKPSGLKPPGRGGKHSSPMGRTST GSASSSAAVAASSKEGSPLHKQSSG PSSSPAAAAAPEKPGPKAAEVGDDF LGDFVVGERVWVNGVKPGVVQYLGE TQFAPGQWAGVVLDDPVGKNDGAVG GVRYFECPALQGIFTRPSKLTRQPT AEGSGSDAHSVESLTAQNLSLHSGT ATPPLTSRVIPLRESVLNSSVKTGN ESGSNLSDSGSVKRGEKDLRLGDRV LVGGTKTGVVRYVGETDFAKGEWCG VELDEPLGKNDGAVAGTRYFQCPPK FGLFAPIHKVIRIGFPSTSPAKAKK TKRMAMGVSALTHSPSSSSISSVSS VASSVGGRPSRSGLLTETSSRYARK ISGTTALQEALKEKQQHIEQLLAER DLERAEVAKATSHICEVEKEIALLK AQHEQYVAEAEEKLQRARLLVESVR KEKVDLSNQLEEERRKVEDLQFRVE EESITKGDLETQTQLEHARIGELEQ SLLLEKAQAERLLRELADNRLTTVA EKSRVLQLEEELTLRRGEIEELQQC LLHSGPPPPDHPDAAEILRLRERLL SASKEHQRESGVLRDKYEKALKAYQ AEVDKLRAANEKYAQEVAGLKDKVQ QATSENMGLMDNWKSKLDSLASDHQ KSLEDLKATLNSGPGAQQKEIGELK AVMEGIKMEHQLELGNLQAKHDLET AMHVKEKEALREKLQEAQEELAGLQ RHWRAQLEVQASQHRLELQEAQDQR RDAELRVHELEKLDVEYRGQAQAIE FLKEQISLAEKKMLDYERLQRAEAQ GKQEVESLREKLLVAENRLQAVEAL CSSQHTHMIESNDISEETIRTKETV EGLQDKLNKRDKEVTALTSQTEMLR AQVSALESKCKSGEKKVDALLKEKR RLEAELETVSRKTHDASGQLVLISQ ELLRKERSLNELRVLLLEANRHSPG PERDLSREVHKAEWRIKEQKLKDDI RGLREKLTGLDKEKSLSDQRRYSLI DPSSAPELLRLQHQLMSTEDALRDA LDQAQQVEKLMEAMRSCPDKAQTIG NSGSANGIHQQDKAQKQEDKHTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |