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Active Recombinant Human CLK3 Protein, GST-tagged

Cat.No. : CLK3-1496H
Product Overview : Human CLK3 (AAH02555.1, 1 a.a. - 490 a.a.) full-length recombinant protein with GST tag expressed in Baculovirus infected Sf21 cells.
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  • Gene Information
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Description : This gene encodes a protein belonging to the serine/threonine type protein kinase family. This protein is a nuclear dual-specificity kinase that regulates the intranuclear distribution of the serine/arginine-rich (SR) family of splicing factors. Two transcript variants encoding different isoforms have been found for this gene. Related pseudogenes are located on chromosomes 1 and 9. [provided by RefSeq, Jul 2008]
Source : Insect Cells
Species : Human
Tag : GST
Form : Liquid
Bio-activity : The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000.Substrate : DYRKtide-F. ATP: 100 µM.
Molecular Mass : 86 kDa
Purity : 88 % by SDS-PAGE/CBB staining.
Applications : Functional Study
SDS-PAGE
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05% Brij35, 1 mM DTT, 10% glycerol)
Gene Name : CLK3 CDC-like kinase 3 [ Homo sapiens ]
Official Symbol : CLK3
Synonyms : CLK3; CDC-like kinase 3; dual specificity protein kinase CLK3; clk3; PHCLK3; PHCLK3/152; FLJ22858;
Gene ID : 1198
mRNA Refseq : NM_001130028
Protein Refseq : NP_001123500
MIM : 602990
UniProt ID : P49761

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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